BZPR_DICDI
ID BZPR_DICDI Reviewed; 897 AA.
AC Q54GH2;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 85.
DE RecName: Full=Probable basic-leucine zipper transcription factor R;
GN Name=bzpR; ORFNames=DDB_G0290165;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [2]
RP IDENTIFICATION.
RX PubMed=16410410; DOI=10.1242/dev.02240;
RA Huang E., Blagg S.L., Keller T., Katoh M., Shaulsky G., Thompson C.R.L.;
RT "bZIP transcription factor interactions regulate DIF responses in
RT Dictyostelium.";
RL Development 133:449-458(2006).
CC -!- FUNCTION: Probable transcriptional regulator. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
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DR EMBL; AAFI02000158; EAL62354.1; -; Genomic_DNA.
DR RefSeq; XP_635856.1; XM_630764.1.
DR AlphaFoldDB; Q54GH2; -.
DR SMR; Q54GH2; -.
DR STRING; 44689.DDB0220092; -.
DR PaxDb; Q54GH2; -.
DR EnsemblProtists; EAL62354; EAL62354; DDB_G0290165.
DR GeneID; 8627512; -.
DR KEGG; ddi:DDB_G0290165; -.
DR dictyBase; DDB_G0290165; bzpR.
DR HOGENOM; CLU_322745_0_0_1; -.
DR OMA; ICEDIPI; -.
DR PRO; PR:Q54GH2; -.
DR Proteomes; UP000002195; Chromosome 5.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0010737; P:protein kinase A signaling; IEP:dictyBase.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0031288; P:sorocarp morphogenesis; IMP:dictyBase.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; SSF57959; 1.
PE 3: Inferred from homology;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..897
FT /note="Probable basic-leucine zipper transcription factor
FT R"
FT /id="PRO_0000383606"
FT DOMAIN 557..620
FT /note="bZIP"
FT REGION 38..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 128..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 461..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 559..564
FT /note="Basic motif"
FT /evidence="ECO:0000250"
FT REGION 569..576
FT /note="Leucine-zipper"
FT /evidence="ECO:0000250"
FT COILED 94..137
FT /evidence="ECO:0000255"
FT COILED 228..258
FT /evidence="ECO:0000255"
FT COILED 330..407
FT /evidence="ECO:0000255"
FT COMPBIAS 461..482
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..506
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 897 AA; 104919 MW; 8AD6565151C8B4DA CRC64;
MDNFENPLLA PDQDVLLYLL DGYSQLQQLQ KQQFNIHDDN INYNNNNNNN NNNNNNNNNN
NNNNNNNNNN NNNNNIGSPQ IMNENIETNS NDPQYLERLQ SIQQQQHQCQ TQIQQQLQNY
QQQYEDQYQQ RQQQYQDQYQ KPYSSPPLNF NSIPPITNNN NNNNNNNNNN NNNNNSNSNS
NSNSNSNSNS NSNSNSNSNN NNINNNICIN NNDISIFLLN NQIQLQPLQQ QQQQQQQQQQ
QQQQQQQQQQ QQQQQQQQPT QPTQPTKPIQ LTQPIQLTQP TLLEELKDIS IQQQLLSAIQ
QTAQSPQQIH PLQQLQPYQL QSYQQIQASQ QLQPYQQLIQ LQQLQLQQLE EEKRQQQKQL
LLQQQQLQEQ QEKLQQQLLQ QQKQQLKQKV KQQKQQHQKQ QPQQQQQSIQ IPPELQNYIL
NNNNNNNNNN TNKTLSPISE MIQNQFLNNQ QTILNQNNST LQLPTPFYSP QQQQQQHTPI
SSFIPPPSLP SSPPSPPSPP SPPPQQQQQQ QQQQQQQQQQ QQQQQQQQQQ QQQQQLQQQQ
LQQQQLQQQH QLKESYESKE SIKKYNQNIA SRNYRLKKKD YIKEIENKIA TLSLENNRLE
KENGSIRTNG SIEMMRMEPE SMKMLMDGKL IIENIKHALI IDDEKSLIYL LHQYHRTIDQ
RYSLLEKEVN KLINPYTQLR LCCIGYVPKS SPLVLNIFQG PESDKWLNLF KIEANITPEQ
SIKIDSLRFQ YGKVSSRLSN ELLELDLIIK RFFIKNVLPT PDTPLLNSDY YSEGELIPNT
TTESIAPLNN FELLDFASKL ESLKNKIILN ASLGLDTFAT LCSILTPKQE ALLLVRVNLF
CIDLHHHDIL GEVWTNVNQI SNSLSNPLTS FSDSMKKINF SFLQLDNNNN NYHYKIN
