ID   BZPS_DICDI              Reviewed;         843 AA.
AC   Q54GG9;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Probable basic-leucine zipper transcription factor S;
GN   Name=bzpS; ORFNames=DDB_G0290171;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=16410410; DOI=10.1242/dev.02240;
RA   Huang E., Blagg S.L., Keller T., Katoh M., Shaulsky G., Thompson C.R.L.;
RT   "bZIP transcription factor interactions regulate DIF responses in
RT   Dictyostelium.";
RL   Development 133:449-458(2006).
CC   -!- FUNCTION: Probable transcriptional regulator. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978}.
CC   -!- SIMILARITY: Belongs to the bZIP family. {ECO:0000305}.
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DR   EMBL; AAFI02000158; EAL62357.1; -; Genomic_DNA.
DR   RefSeq; XP_635859.1; XM_630767.1.
DR   AlphaFoldDB; Q54GG9; -.
DR   PaxDb; Q54GG9; -.
DR   PRIDE; Q54GG9; -.
DR   EnsemblProtists; EAL62357; EAL62357; DDB_G0290171.
DR   GeneID; 8627515; -.
DR   KEGG; ddi:DDB_G0290171; -.
DR   dictyBase; DDB_G0290171; bzpS.
DR   HOGENOM; CLU_337849_0_0_1; -.
DR   PRO; PR:Q54GG9; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR004827; bZIP.
DR   InterPro; IPR046347; bZIP_sf.
DR   Pfam; PF00170; bZIP_1; 1.
DR   SMART; SM00338; BRLZ; 1.
DR   SUPFAM; SSF57959; SSF57959; 1.
DR   PROSITE; PS50217; BZIP; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..843
FT                   /note="Probable basic-leucine zipper transcription factor
FT                   S"
FT                   /id="PRO_0000383607"
FT   DOMAIN          517..580
FT                   /note="bZIP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT   REGION          27..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          298..347
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          430..478
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          519..520
FT                   /note="Basic motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
FT   REGION          522..529
FT                   /note="Leucine-zipper"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
SQ   SEQUENCE   843 AA;  95910 MW;  858E0EDAEF5E73B2 CRC64;
     MDSKNPLPTP EKNIWSLLLK DFSQLQQNQF QKSQQPQQQN NTNINLNQNN IINNNNNNDN
     LNTINNNNTI NNNNNNNNNN NNNNNNNNNN NNDNLNTINN IISNIINNNS NNVNLNNIIN
     NNNNSNNINK NNNNNNNNVN LNNIINNNNV NLNNNSINYN NSNNENSINN INYNNENSIN
     NNNNNNNNFI NDIYNDVNNN NNNNGNNTYD QQVLMEQLQL LEQLQQQQHT IQQHLRGYQH
     QCQKQYEQRQ QDYQQQYQQP YISPSSLLIT SDDNQIDYNQ LLSGNNINII NYLSENNQQP
     QTLPQSTPIS PQLQTQSQVA PQQKQLLQQQ QQQNVDPPPI SQSPSYSSIA SFSIGDQVNN
     NINNNNNNNS QFFPILPTNV DILQQSNLNK LPIDFINNNN INIEKLIMYN NNNNSILSNN
     TTPTLTPTVT PTLTPTVTPT LTPTVTPTLT STPSNSTSIS TTTTNSTLKP NSKTTTTNTK
     TITKLNKNET GNLDQTNLQN SKIVPIDLSL QIPIDSPSRK SLKKINQNIA SRNYRQKKKD
     YIKEIEERML ALSIENDKLH KENESLKKIG GAEAMKLGPE LMKLMVDGNK ILLEMKKCLD
     INDERTLIYL LHQYHCVVEK RYLYMEKEVD KVANPYTQMR LAKVGYTPKQ SLSGINIFQG
     PEADSWINLF KKEVNITLEQ SNKLDSLRAQ YCAVSEKIQF DLEKLDSEIK TFFFEKVFAL
     QLGNDITDNN IEGIPASKVL PIEIFGPLDL NEQLDIINKL ETLKNKLTLN CSLFLDTFSS
     ISAILTPKQE AVLLTKVNIF ACANSLDFEL VKDVWSNIIQ NSFSGPIDIG ETLKKLFRNP
     TNQ