ID   TRPBP_PSEAE             Reviewed;         532 AA.
AC   Q9HVS4;
DT   23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Tripeptide-binding protein {ECO:0000305};
DE   Flags: Precursor;
GN   OrderedLocusNames=PA4497 {ECO:0000312|EMBL:AAG07885.1};
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
RN   [2]
RP   FUNCTION AS A BINDING PROTEIN.
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=31627455; DOI=10.3390/ijms20205156;
RA   Fernandez M., Rico-Jimenez M., Ortega A., Daddaoua A., Garcia Garcia A.I.,
RA   Martin-Mora D., Torres N.M., Tajuelo A., Matilla M.A., Krell T.;
RT   "Determination of Ligand Profiles for Pseudomonas aeruginosa Solute Binding
RT   Proteins.";
RL   Int. J. Mol. Sci. 20:5156-5156(2019).
CC   -!- FUNCTION: Binds different tripeptides. Probably recognizes specifically
CC       tripeptides composed exclusively of L-amino acids.
CC       {ECO:0000269|PubMed:31627455}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 5 family.
CC       {ECO:0000305}.
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DR   EMBL; AE004091; AAG07885.1; -; Genomic_DNA.
DR   PIR; H83083; H83083.
DR   RefSeq; NP_253187.1; NC_002516.2.
DR   RefSeq; WP_003112862.1; NZ_QZGE01000004.1.
DR   AlphaFoldDB; Q9HVS4; -.
DR   SMR; Q9HVS4; -.
DR   STRING; 287.DR97_1676; -.
DR   PaxDb; Q9HVS4; -.
DR   EnsemblBacteria; AAG07885; AAG07885; PA4497.
DR   GeneID; 881082; -.
DR   KEGG; pae:PA4497; -.
DR   PATRIC; fig|208964.12.peg.4707; -.
DR   PseudoCAP; PA4497; -.
DR   HOGENOM; CLU_017028_7_0_6; -.
DR   InParanoid; Q9HVS4; -.
DR   OMA; YIPLTYQ; -.
DR   PhylomeDB; Q9HVS4; -.
DR   BioCyc; PAER208964:G1FZ6-4586-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IBA:GO_Central.
DR   GO; GO:1904680; F:peptide transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0042938; P:dipeptide transport; IBA:GO_Central.
DR   GO; GO:0015833; P:peptide transport; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR030678; Peptide/Ni-bd.
DR   InterPro; IPR039424; SBP_5.
DR   InterPro; IPR000914; SBP_5_dom.
DR   PANTHER; PTHR30290; PTHR30290; 1.
DR   Pfam; PF00496; SBP_bac_5; 1.
DR   PIRSF; PIRSF002741; MppA; 1.
PE   1: Evidence at protein level;
KW   Peptide transport; Periplasm; Protein transport; Reference proteome;
KW   Signal; Transport.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..532
FT                   /note="Tripeptide-binding protein"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_5004326824"
SQ   SEQUENCE   532 AA;  59497 MW;  6C11C50B7525F609 CRC64;
     MRPRSALRYS LLLLALAASA AIQAQPKTLA VCTEAAPEGF DPARYTSGYT FDASAHPLYN
     ALAAFAPGSA TVIPALAESW DVSADGLVYT FRLRQGVKFH STDYFKPTRE FDADDVLFSF
     QRMLDPQHPA HDLSPSGYPY ADAMQLRDII ERIEKIDEHQ VRFVLKHPEA PFLADLAMPF
     GSILSAEYAG QLIARGKGDE LNSKPIGTGP FVFTRYRKDA QVRYAANPDY WKGKPAIDHL
     VLAITLDPNV RVQRLRRNEC QIALTPKPED VAALRQDPQL TVLEEAAMIT SHAAINTRHE
     PFDDPRVRRA IAMGFNKSSY LKIVFGDQAR PAIGPYPPML LGYDDSIRDW PYDPERAKAL
     LKEAGVTPDT PLNLYISTGS GPGGNPARVA QLIQSDLAAI GIRVNIRQFE WGEMVKRTKA
     GEHDMMLYSW IGDNGDPDNF LTHNLGCASV ESGENRARWC DKGFDEAIRK ARMSNDESQR
     VALYKEAQRI FHEQMPWLPL AHPLMFDAQR KNVSGYRMSP MSARDFSRVK LD