ID   C124A_XENLA             Reviewed;         217 AA.
AC   Q68EY7;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Coiled-coil domain-containing protein 124-A;
GN   Name=ccdc124-a;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for proper progression of late cytokinetic stages.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with RASGEF1B. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000250}. Midbody {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CCDC124 family. {ECO:0000305}.
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DR   EMBL; BC080061; AAH80061.1; -; mRNA.
DR   RefSeq; NP_001087524.1; NM_001094055.1.
DR   RefSeq; XP_018103246.1; XM_018247757.1.
DR   RefSeq; XP_018103254.1; XM_018247765.1.
DR   AlphaFoldDB; Q68EY7; -.
DR   SMR; Q68EY7; -.
DR   BioGRID; 104208; 1.
DR   IntAct; Q68EY7; 1.
DR   MaxQB; Q68EY7; -.
DR   DNASU; 447348; -.
DR   GeneID; 447348; -.
DR   KEGG; xla:447348; -.
DR   CTD; 447348; -.
DR   Xenbase; XB-GENE-1015203; ccdc124.L.
DR   OMA; RHPEKRM; -.
DR   OrthoDB; 1585903at2759; -.
DR   Proteomes; UP000186698; Chromosome 1L.
DR   Bgee; 447348; Expressed in muscle tissue and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
DR   GO; GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   InterPro; IPR010422; Ccdc124/Oxs1.
DR   PANTHER; PTHR21680; PTHR21680; 1.
DR   Pfam; PF06244; Ccdc124; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Coiled coil; Cytoplasm; Cytoskeleton;
KW   Reference proteome.
FT   CHAIN           1..217
FT                   /note="Coiled-coil domain-containing protein 124-A"
FT                   /id="PRO_0000263739"
FT   REGION          1..128
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          46..82
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        14..84
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        98..128
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   217 AA;  25260 MW;  4643A13E9F206361 CRC64;
     MPKKFQGENT KSAVARARKA EAKAVSDGKR QKEIEDAYWQ DDDKHVARKG QRKEDKEKKR
     LEQLERKKES QRLLDEEDSK MKAKPTKPAA PSKVTRAEIE ETLCKEEEHK ATTEKPKTHL
     EMPLEENVNR RVLEEGEVEA RTVEDAIAAL SVGKELDRHP ERRMKAAFAA FEEINMPLLK
     QENPNMRLSQ LKHLLKKEWM KSPENPMNQQ HAMYNSH