ID   C124B_XENLA             Reviewed;         217 AA.
AC   Q6DD17;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Coiled-coil domain-containing protein 124-B;
GN   Name=ccdc124-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for proper progression of late cytokinetic stages.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with RASGEF1B. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center, centrosome {ECO:0000250}. Midbody {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CCDC124 family. {ECO:0000305}.
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DR   EMBL; BC077812; AAH77812.1; -; mRNA.
DR   RefSeq; NP_001086949.1; NM_001093480.1.
DR   RefSeq; XP_018095323.1; XM_018239834.1.
DR   AlphaFoldDB; Q6DD17; -.
DR   SMR; Q6DD17; -.
DR   DNASU; 446784; -.
DR   GeneID; 446784; -.
DR   KEGG; xla:446784; -.
DR   CTD; 446784; -.
DR   Xenbase; XB-GENE-6255345; ccdc124.S.
DR   OrthoDB; 1585903at2759; -.
DR   Proteomes; UP000186698; Chromosome 1S.
DR   Bgee; 446784; Expressed in muscle tissue and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
DR   GO; GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   InterPro; IPR010422; Ccdc124/Oxs1.
DR   PANTHER; PTHR21680; PTHR21680; 1.
DR   Pfam; PF06244; Ccdc124; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Coiled coil; Cytoplasm; Cytoskeleton;
KW   Reference proteome.
FT   CHAIN           1..217
FT                   /note="Coiled-coil domain-containing protein 124-B"
FT                   /id="PRO_0000263740"
FT   REGION          1..123
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          41..83
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        14..84
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        99..123
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   217 AA;  25347 MW;  D0EC1569AB2FC64A CRC64;
     MPKKFQSENT KSAAARARKA EAKAVADAKR KKETEDAFWQ DDDKHVVRKE HRKEEKEKKR
     LELLERKKES QRLLDEEDSK MKGKPTKPAA PSKVTRAQIE ETLCKEEKHK DAPEKPKTHL
     EIPLEENVNR RVLEEGEVEA RTVEDAIAAL SIGKELDRHP ERRMKAAFTA FEEINMPLLK
     QENPNMRLSQ LKQLLKKEWM KSPENPMNQK YATYNSH