ID   C1332_XYLFT             Reviewed;         399 AA.
AC   Q87AV9;
DT   16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Putative cytochrome P450 133B2;
DE            EC=1.14.-.-;
GN   Name=cyp133B2; OrderedLocusNames=PD_1704;
OS   Xylella fastidiosa (strain Temecula1 / ATCC 700964).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Xylella.
OX   NCBI_TaxID=183190;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Temecula1 / ATCC 700964;
RX   PubMed=12533478; DOI=10.1128/jb.185.3.1018-1026.2003;
RA   Van Sluys M.A., de Oliveira M.C., Monteiro-Vitorello C.B., Miyaki C.Y.,
RA   Furlan L.R., Camargo L.E.A., da Silva A.C.R., Moon D.H., Takita M.A.,
RA   Lemos E.G.M., Machado M.A., Ferro M.I.T., da Silva F.R., Goldman M.H.S.,
RA   Goldman G.H., Lemos M.V.F., El-Dorry H., Tsai S.M., Carrer H.,
RA   Carraro D.M., de Oliveira R.C., Nunes L.R., Siqueira W.J., Coutinho L.L.,
RA   Kimura E.T., Ferro E.S., Harakava R., Kuramae E.E., Marino C.L.,
RA   Giglioti E., Abreu I.L., Alves L.M.C., do Amaral A.M., Baia G.S.,
RA   Blanco S.R., Brito M.S., Cannavan F.S., Celestino A.V., da Cunha A.F.,
RA   Fenille R.C., Ferro J.A., Formighieri E.F., Kishi L.T., Leoni S.G.,
RA   Oliveira A.R., Rosa V.E. Jr., Sassaki F.T., Sena J.A.D., de Souza A.A.,
RA   Truffi D., Tsukumo F., Yanai G.M., Zaros L.G., Civerolo E.L.,
RA   Simpson A.J.G., Almeida N.F. Jr., Setubal J.C., Kitajima J.P.;
RT   "Comparative analyses of the complete genome sequences of Pierce's disease
RT   and citrus variegated chlorosis strains of Xylella fastidiosa.";
RL   J. Bacteriol. 185:1018-1026(2003).
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
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DR   EMBL; AE009442; AAO29542.1; -; Genomic_DNA.
DR   RefSeq; WP_011098220.1; NC_004556.1.
DR   AlphaFoldDB; Q87AV9; -.
DR   SMR; Q87AV9; -.
DR   EnsemblBacteria; AAO29542; AAO29542; PD_1704.
DR   GeneID; 58017222; -.
DR   KEGG; xft:PD_1704; -.
DR   HOGENOM; CLU_033716_0_2_6; -.
DR   OMA; RPELWPN; -.
DR   Proteomes; UP000002516; Chromosome.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   Gene3D; 1.10.630.10; -; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR002397; Cyt_P450_B.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00359; BP450.
DR   SUPFAM; SSF48264; SSF48264; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase.
FT   CHAIN           1..399
FT                   /note="Putative cytochrome P450 133B2"
FT                   /id="PRO_0000052291"
FT   BINDING         348
FT                   /ligand="heme"
FT                   /ligand_id="ChEBI:CHEBI:30413"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="axial binding residue"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   399 AA;  44684 MW;  34F298EE726A378E CRC64;
     MKLADLSSPA FLENPYPLYE TLRRQGPFVS IGPNALMTGR YSIVDGLLHN RNMGKSYMES
     IRVRYGDDAL DMPLFQGFNR MFLMLNPPVH THLRGLVMQA FTGRESESMR PLAIDTAHRL
     IDDFEQKSSV DLVTEFSFPL PMRIICRMMD VDISDAISLS VAVSNLAKVF DPAPMSPDEL
     VHASAAYEEL AHYFTRLIEL RRAQHGTDLI SMLLRAEEEG QKLTHDEIVS NVILLLLGGY
     ETTSNMIGNA LIALHRHPKQ LARLKSDLSL MPQAVLECLR YDGSVQFTIR AAMDDVSIEG
     DVVPRGTIVF LMLGAANRDP AQFTDPDHLE ITRKQGRLQS FGAGVHHCLG YRLALVELEC
     ALTVLLERLP HLRLANLDTL SWNQRGNLRG VNALIADLH