ID   C144C_HUMAN             Reviewed;        1237 AA.
AC   Q8IYA2; B7WNP5;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 3.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Putative coiled-coil domain-containing protein 144C;
DE   AltName: Full=Coiled-coil domain-containing protein 144C pseudogene;
GN   Name=CCDC144CP; Synonyms=CCDC144C;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S.,
RA   Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E.,
RA   Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K.,
RA   LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J.,
RA   Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A.,
RA   Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K.,
RA   Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in the
RT   human lineage.";
RL   Nature 440:1045-1049(2006).
CC   -!- SIMILARITY: Belongs to the CCDC144 family. {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR   EMBL; AC008088; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC015818; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; Q8IYA2; -.
DR   SMR; Q8IYA2; -.
DR   iPTMnet; Q8IYA2; -.
DR   PhosphoSitePlus; Q8IYA2; -.
DR   BioMuta; HGNC:29073; -.
DR   DMDM; 162416239; -.
DR   jPOST; Q8IYA2; -.
DR   MassIVE; Q8IYA2; -.
DR   MaxQB; Q8IYA2; -.
DR   PeptideAtlas; Q8IYA2; -.
DR   PRIDE; Q8IYA2; -.
DR   ProteomicsDB; 71131; -.
DR   GeneCards; CCDC144CP; -.
DR   HGNC; HGNC:29073; CCDC144CP.
DR   neXtProt; NX_Q8IYA2; -.
DR   InParanoid; Q8IYA2; -.
DR   PhylomeDB; Q8IYA2; -.
DR   ChiTaRS; CCDC144CP; human.
DR   Pharos; Q8IYA2; Tdark.
DR   PRO; PR:Q8IYA2; -.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q8IYA2; protein.
DR   InterPro; IPR040118; C144A/B/C.
DR   InterPro; IPR039497; CC144C-like_CC_dom.
DR   InterPro; IPR021885; DUF3496.
DR   PANTHER; PTHR22245; PTHR22245; 2.
DR   Pfam; PF14915; CCDC144C; 1.
DR   Pfam; PF12001; DUF3496; 1.
PE   5: Uncertain;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..1237
FT                   /note="Putative coiled-coil domain-containing protein 144C"
FT                   /id="PRO_0000312281"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          120..181
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          403..435
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          479..519
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          440..595
FT                   /evidence="ECO:0000255"
FT   COILED          636..939
FT                   /evidence="ECO:0000255"
FT   COILED          965..1042
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        121..153
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        403..422
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        488..507
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1237 AA;  143112 MW;  E18417A167348457 CRC64;
     MVSWGGEKRG GAEGSPKPAV YATRKTGSVR SQEDQWYLGY PGDQWSSGFS YSWWKNSVGS
     ESKHGEGALD QPQHDVRLED LGELHRAARS GDVPGVEHVL VPGDTGVDKR DRKKSIQQLV
     PEYKEKQTPE SLPQNNNPDW HPTNLTLSDE TCQRSKNLKV DDKCPSVSPS MPENQSATKE
     LGQMNLTERE KMDTGVKTSQ EPEMAKDCDR EDIPIYPVLP HVQKSEEMRI EQGKLEWKNQ
     LKLVINELKQ RFGEIYEKYK IPACPEEEPL LDNSTRGTDV KDIPFNLTNN IPGCEEEDAS
     EISVSVVFET FPEQKEPSLK NIIHSYYHPY SGSQEHVCQS SSKLHLHENK LDCDNDNKPG
     IGHIFSTDKN FHNDASTKKA RNPEVVTVEM KEDQEFDLQM TKNMNQNSDS GSTNNYKSLK
     PKLENLSSLP PDSDRTSEVY LHEELQQDMQ KFKNEVNTLE EEFLALKKEN VQLHKEVEEE
     MEKHRSNSTE LSGTLTDGTT VGNDDDGLNQ QIPRKENGEH DRLALKQENE EKRNADMLYN
     KDSEQLRIKE EECGKVVETK QQLKWNLRRL VKELRTVVQE RNDAQKQLSE EQDARILQDQ
     ILTSKQKELE MAQKKRNPEI SHRHQKEKDL FHENCMLQEE IALLRLEIDT IKNQNKQKEK
     KYFEDIEVVK EKNDNLQKII KRNEETLTET ILQYSGQLNN LTAENKMLNS ELENGKENQE
     RLEIEMESYR CRLAAAVHDC DQSQTARDLK LDFQRTRQEW VRLHDKMKVD MSGLQAKNEI
     LSEKLSNAES KINSLQIQLH NTRDALGRES LILERVQRDL SQTQCQKKET EQMYQSKLKK
     YIAKQESVEE RLSQLQSENM LLRQQLDDVH KKANSQEKTI STIQDQFHSA AKNLQAESEK
     QILSLQEKNK ELMDEYNHLK ERMDQCEKEK AGRKIDLTEA QETVPSRCLH LDAENEVLQL
     QQTLFSMKAI QKQCETLQKN KKQLKQEVVN LKSYMERNML ERGEAEWHKL LIEERARKEI
     EEKLNEAILT LQKQAAVSHE QLAQLREDNT TSIKTQMELT VIDLESEISR IKTSQADFNK
     TKLERYKELY LEEVKVRESL SNELSRTNEM IAEVSTQLTV EKEQTRSRSL FTAYATRPVL
     ESPCVGNLND SEGLNRKHIP RKKRSALKDM ESYLLKMQQK LQNDLTAEVA GSSQTGLHRI
     PQCSSFSSSS LHLLLCSICQ PFFLILQLLL NMNLDPI