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C144L_HUMAN
ID   C144L_HUMAN             Reviewed;         221 AA.
AC   Q6NUI1;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Putative coiled-coil domain-containing protein 144 N-terminal-like;
GN   Name=CCDC144NL;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the CCDC144 family. {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. Shares high sequence
CC       similarity with the N-terminus of the CCDC144 family. Compared to other
CC       members of the family, it is however much shorter and lacks the C-
CC       terminal part. {ECO:0000305}.
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DR   EMBL; BC068597; AAH68597.1; -; mRNA.
DR   RefSeq; NP_001004306.1; NM_001004306.2.
DR   AlphaFoldDB; Q6NUI1; -.
DR   BioGRID; 130837; 1.
DR   STRING; 9606.ENSP00000328054; -.
DR   iPTMnet; Q6NUI1; -.
DR   PhosphoSitePlus; Q6NUI1; -.
DR   BioMuta; CCDC144NL; -.
DR   MassIVE; Q6NUI1; -.
DR   PaxDb; Q6NUI1; -.
DR   PeptideAtlas; Q6NUI1; -.
DR   PRIDE; Q6NUI1; -.
DR   UCSC; uc002gyf.3; human.
DR   GeneCards; CCDC144NL; -.
DR   HGNC; HGNC:33735; CCDC144NL.
DR   neXtProt; NX_Q6NUI1; -.
DR   PharmGKB; PA164717677; -.
DR   eggNOG; ENOG502TEIQ; Eukaryota.
DR   HOGENOM; CLU_1250307_0_0_1; -.
DR   InParanoid; Q6NUI1; -.
DR   OrthoDB; 1707774at2759; -.
DR   PhylomeDB; Q6NUI1; -.
DR   PathwayCommons; Q6NUI1; -.
DR   SignaLink; Q6NUI1; -.
DR   BioGRID-ORCS; 339184; 137 hits in 997 CRISPR screens.
DR   ChiTaRS; CCDC144NL; human.
DR   GenomeRNAi; 339184; -.
DR   Pharos; Q6NUI1; Tdark.
DR   Proteomes; UP000005640; Chromosome 17.
DR   RNAct; Q6NUI1; protein.
PE   5: Uncertain;
KW   Reference proteome.
FT   CHAIN           1..221
FT                   /note="Putative coiled-coil domain-containing protein 144
FT                   N-terminal-like"
FT                   /id="PRO_0000346158"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          89..151
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        103..120
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        121..142
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VARIANT         82
FT                   /note="G -> D (in dbSNP:rs7216787)"
FT                   /id="VAR_045892"
SQ   SEQUENCE   221 AA;  23810 MW;  27D58E9C59EB118B CRC64;
     MASWGGEKRG GAGGSPKPAV YATRKTPSVG SQEDQWYLDY PGDQWSLGFS YSWWKNSVGS
     ESKHGEGALD QLQHDVRLED LGELHRAARS GDVPGVEHVL APGDTGVDKR DRKKSIQQLV
     PEYKEKQTPE SLPQNNNPAA PSQAEGGEGG VACGTVEQMT WLCSLPHAVG GGDGDHSSTG
     AVGGHPRGPG EYCHLHEQRV HHHIFARGKR KGKNHVSNVV R
 
 
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