C144L_HUMAN
ID C144L_HUMAN Reviewed; 221 AA.
AC Q6NUI1;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Putative coiled-coil domain-containing protein 144 N-terminal-like;
GN Name=CCDC144NL;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the CCDC144 family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. Shares high sequence
CC similarity with the N-terminus of the CCDC144 family. Compared to other
CC members of the family, it is however much shorter and lacks the C-
CC terminal part. {ECO:0000305}.
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DR EMBL; BC068597; AAH68597.1; -; mRNA.
DR RefSeq; NP_001004306.1; NM_001004306.2.
DR AlphaFoldDB; Q6NUI1; -.
DR BioGRID; 130837; 1.
DR STRING; 9606.ENSP00000328054; -.
DR iPTMnet; Q6NUI1; -.
DR PhosphoSitePlus; Q6NUI1; -.
DR BioMuta; CCDC144NL; -.
DR MassIVE; Q6NUI1; -.
DR PaxDb; Q6NUI1; -.
DR PeptideAtlas; Q6NUI1; -.
DR PRIDE; Q6NUI1; -.
DR UCSC; uc002gyf.3; human.
DR GeneCards; CCDC144NL; -.
DR HGNC; HGNC:33735; CCDC144NL.
DR neXtProt; NX_Q6NUI1; -.
DR PharmGKB; PA164717677; -.
DR eggNOG; ENOG502TEIQ; Eukaryota.
DR HOGENOM; CLU_1250307_0_0_1; -.
DR InParanoid; Q6NUI1; -.
DR OrthoDB; 1707774at2759; -.
DR PhylomeDB; Q6NUI1; -.
DR PathwayCommons; Q6NUI1; -.
DR SignaLink; Q6NUI1; -.
DR BioGRID-ORCS; 339184; 137 hits in 997 CRISPR screens.
DR ChiTaRS; CCDC144NL; human.
DR GenomeRNAi; 339184; -.
DR Pharos; Q6NUI1; Tdark.
DR Proteomes; UP000005640; Chromosome 17.
DR RNAct; Q6NUI1; protein.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..221
FT /note="Putative coiled-coil domain-containing protein 144
FT N-terminal-like"
FT /id="PRO_0000346158"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 89..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..120
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VARIANT 82
FT /note="G -> D (in dbSNP:rs7216787)"
FT /id="VAR_045892"
SQ SEQUENCE 221 AA; 23810 MW; 27D58E9C59EB118B CRC64;
MASWGGEKRG GAGGSPKPAV YATRKTPSVG SQEDQWYLDY PGDQWSLGFS YSWWKNSVGS
ESKHGEGALD QLQHDVRLED LGELHRAARS GDVPGVEHVL APGDTGVDKR DRKKSIQQLV
PEYKEKQTPE SLPQNNNPAA PSQAEGGEGG VACGTVEQMT WLCSLPHAVG GGDGDHSSTG
AVGGHPRGPG EYCHLHEQRV HHHIFARGKR KGKNHVSNVV R