C14C1_ORYSJ
ID C14C1_ORYSJ Reviewed; 503 AA.
AC B9GBJ9; Q0IQI6; Q2QYH8;
DT 29-MAY-2013, integrated into UniProtKB/Swiss-Prot.
DT 24-MAR-2009, sequence version 1.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=Cytochrome P450 714C1;
DE EC=1.14.-.-;
GN Name=CYP714C1; OrderedLocusNames=Os12g0118900, LOC_Os12g02630;
GN ORFNames=OsJ_35024;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 198-503.
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP IDENTIFICATION.
RX PubMed=19951895; DOI=10.1186/1479-7364-4-1-59;
RA Nelson D.R.;
RT "The cytochrome p450 homepage.";
RL Hum. Genomics 4:59-65(2009).
RN [8]
RP FUNCTION.
RX PubMed=23319637; DOI=10.1073/pnas.1215788110;
RA Magome H., Nomura T., Hanada A., Takeda-Kamiya N., Ohnishi T., Shinma Y.,
RA Katsumata T., Kawaide H., Kamiya Y., Yamaguchi S.;
RT "CYP714B1 and CYP714B2 encode gibberellin 13-oxidases that reduce
RT gibberellin activity in rice.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:1947-1952(2013).
CC -!- FUNCTION: Probably not involved in gibberellin metabolism since over-
CC expression of CYP714C1 in a heterologous system does not induce semi-
CC dwarfism. {ECO:0000269|PubMed:23319637}.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type III
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABA95659.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAF29029.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAG88413.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; DP000011; ABA95659.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008218; BAF29029.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014968; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM000149; EEE52656.1; -; Genomic_DNA.
DR EMBL; AK062692; BAG88413.1; ALT_INIT; mRNA.
DR RefSeq; XP_015619748.1; XM_015764262.1.
DR AlphaFoldDB; B9GBJ9; -.
DR SMR; B9GBJ9; -.
DR STRING; 4530.OS12T0118900-01; -.
DR PaxDb; B9GBJ9; -.
DR PRIDE; B9GBJ9; -.
DR GeneID; 4351345; -.
DR KEGG; osa:4351345; -.
DR eggNOG; KOG0157; Eukaryota.
DR HOGENOM; CLU_001570_5_0_1; -.
DR InParanoid; B9GBJ9; -.
DR OrthoDB; 825914at2759; -.
DR Proteomes; UP000000763; Chromosome 12.
DR Proteomes; UP000007752; Chromosome 12.
DR Proteomes; UP000059680; Chromosome 12.
DR Genevisible; B9GBJ9; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IBA:GO_Central.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR Gene3D; 1.10.630.10; -; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; SSF48264; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 2: Evidence at transcript level;
KW Heme; Iron; Membrane; Metal-binding; Monooxygenase; Oxidoreductase;
KW Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix.
FT CHAIN 1..503
FT /note="Cytochrome P450 714C1"
FT /id="PRO_0000422415"
FT TOPO_DOM 1..6
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 7..27
FT /note="Helical; Signal-anchor for type III membrane
FT protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 28..503
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT BINDING 450
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000250"
SQ SEQUENCE 503 AA; 56723 MW; 673F6A55BCBA9272 CRC64;
MEKLLALIVV LVILLSLALF YLCNILWLRA VKIRKKLRRQ GIRGPKPTFL YGNTKEIKRI
RQELKFSQKQ GTNNFISTLF PHFLLCRETY GPVFLYSTGA LEILQVSHPD MVKDIGRWTP
SELGKPNYLK KSRKALFGGG LFTENGDEWA YQRKIIAPEF FMDKIKGMIQ LIEDATVTVL
EAWEDMIDDV GGCREIVVDD YLRNLSADVI ARACFGSSFT KGEEIFCKLR QLQKVIAQQD
SFVGLSALWK YLPTKSNQEI QMLDEQVRLL ILDVAKEQHH YQDSHNSLVN AIIDGAQDGR
SAAEAEDFIV GNCKTIYFGG HESTAVTAIW CLMLLATHSE AMEVCRGRST LDVDALRRLK
IVTMVIQETL RLYPPASVMM QEALTDVKLG NIEVPRGTIV QVPRLMLHLD KEAWGADADE
FRPDRFANGV AAACRAAHMY VPFGHGPRTC IGQNLAMAEL KVVLARLLTK FAFSPSPRYR
HSPAFRLTIE PGFGLPLMVT KLP
