ID   C15AA_BACUT             Reviewed;         340 AA.
AC   Q45729;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Pesticidal crystal protein Cry15Aa;
DE   AltName: Full=38 kDa crystal protein;
DE   AltName: Full=Crystaline entomocidal protoxin;
DE   AltName: Full=Insecticidal delta-endotoxin CryXVA(a);
GN   Name=cry15Aa; Synonyms=cryXVA(a);
OS   Bacillus thuringiensis subsp. thompsoni.
OG   Plasmid.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=44162;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1729243; DOI=10.1128/jb.174.2.549-557.1992;
RA   Brown K.L., Whiteley H.R.;
RT   "Molecular characterization of two novel crystal protein genes from
RT   Bacillus thuringiensis subsp. thompsoni.";
RL   J. Bacteriol. 174:549-557(1992).
CC   -!- FUNCTION: Promotes colloidosmotic lysis by binding to the midgut
CC       epithelial cells of lepidopteran larvae.
CC   -!- DEVELOPMENTAL STAGE: The crystal protein is produced during sporulation
CC       and is accumulated both as an inclusion and as part of the spore coat.
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DR   EMBL; M76442; AAA22333.1; -; Genomic_DNA.
DR   PIR; B41969; B41969.
DR   AlphaFoldDB; Q45729; -.
DR   SMR; Q45729; -.
DR   TCDB; 1.C.78.1.1; the crystal protein (cry) family.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   InterPro; IPR004991; Aerolysin-like.
DR   InterPro; IPR011218; Insecticidal_delta_endotoxin.
DR   Pfam; PF03318; ETX_MTX2; 1.
DR   PIRSF; PIRSF026584; Delta_tox; 1.
PE   2: Evidence at transcript level;
KW   Plasmid; Sporulation; Toxin; Virulence.
FT   CHAIN           1..340
FT                   /note="Pesticidal crystal protein Cry15Aa"
FT                   /id="PRO_0000174088"
FT   REGION          318..340
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   340 AA;  37547 MW;  BCBFA24FE9B1FA50 CRC64;
     MAIMNDIAQD AARAWDIIAG PFIRPGTTPT NRQLFNYQIG NIEVEPGNLN FSVVPELDFS
     VSQDLFNNTS VQQSQTASFN ESRTETTSTA VTHGVKSGVT VSASAKFNAK ILVKSIEQTI
     TTTVSTEYNF SSTTTRTNTV TRGWSIAQPV LVPPHSRVTA TLQIYKGDFT VPVLLSLRVY
     GQTGTLAGNP SFPSLYAATY ENTLLGRIRE HIAPPALFRA SNAYISNGVQ AIWRGTATTR
     VSQGLYSVVR IDERPLAGYS GETRTYYLPV TLSNSSQILT PGSLGSEIPI INPVPNASCK
     KENSPIIIHH DREKHRERDY DKEHICHDQA EKYERDYDKE