C170L_HUMAN
ID C170L_HUMAN Reviewed; 293 AA.
AC Q96L14;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2004, sequence version 2.
DT 25-MAY-2022, entry version 116.
DE RecName: Full=Cep170-like protein;
DE AltName: Full=CEP170 pseudogene 1;
GN Name=CEP170P1; Synonyms=CEP170L, KIAA0470L;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15815621; DOI=10.1038/nature03466;
RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA Wilson R.K.;
RT "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT 4.";
RL Nature 434:724-731(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q96L14; Q13155: AIMP2; NbExp=5; IntAct=EBI-743488, EBI-745226;
CC Q96L14; Q99819: ARHGDIG; NbExp=3; IntAct=EBI-743488, EBI-10295284;
CC Q96L14; Q96HB5-4: CCDC120; NbExp=4; IntAct=EBI-743488, EBI-10185348;
CC Q96L14; Q8IYE0-2: CCDC146; NbExp=3; IntAct=EBI-743488, EBI-10247802;
CC Q96L14; Q9BU64: CENPO; NbExp=5; IntAct=EBI-743488, EBI-745954;
CC Q96L14; Q96L14: CEP170P1; NbExp=3; IntAct=EBI-743488, EBI-743488;
CC Q96L14; Q8NHS4: CLHC1; NbExp=3; IntAct=EBI-743488, EBI-10203156;
CC Q96L14; Q96CS2: HAUS1; NbExp=3; IntAct=EBI-743488, EBI-2514791;
CC Q96L14; Q9BVG8: KIFC3; NbExp=4; IntAct=EBI-743488, EBI-2125614;
CC Q96L14; P25800: LMO1; NbExp=3; IntAct=EBI-743488, EBI-8639312;
CC Q96L14; P61968: LMO4; NbExp=3; IntAct=EBI-743488, EBI-2798728;
CC Q96L14; O43482: OIP5; NbExp=3; IntAct=EBI-743488, EBI-536879;
CC Q96L14; Q969G3: SMARCE1; NbExp=3; IntAct=EBI-743488, EBI-455078;
CC Q96L14; A1L4H1: SSC5D; NbExp=3; IntAct=EBI-743488, EBI-10172867;
CC Q96L14; E2PSM9; NbExp=3; IntAct=EBI-743488, EBI-10176929;
CC -!- SIMILARITY: Belongs to the CEP170 family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR EMBL; AC092670; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC014590; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; Q96L14; -.
DR IntAct; Q96L14; 100.
DR BioMuta; HGNC:28364; -.
DR DMDM; 74751998; -.
DR EPD; Q96L14; -.
DR jPOST; Q96L14; -.
DR MassIVE; Q96L14; -.
DR MaxQB; Q96L14; -.
DR PeptideAtlas; Q96L14; -.
DR PRIDE; Q96L14; -.
DR ProteomicsDB; 77138; -.
DR GeneCards; CEP170P1; -.
DR HGNC; HGNC:28364; CEP170P1.
DR neXtProt; NX_Q96L14; -.
DR InParanoid; Q96L14; -.
DR PhylomeDB; Q96L14; -.
DR PathwayCommons; Q96L14; -.
DR SignaLink; Q96L14; -.
DR Pharos; Q96L14; Tdark.
DR PRO; PR:Q96L14; -.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q96L14; protein.
DR GO; GO:0005814; C:centriole; IBA:GO_Central.
DR GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR InterPro; IPR026644; CEP170.
DR InterPro; IPR029300; CEP170_C.
DR PANTHER; PTHR15715:SF17; PTHR15715:SF17; 1.
DR Pfam; PF15308; CEP170_C; 1.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..293
FT /note="Cep170-like protein"
FT /id="PRO_0000343425"
FT REGION 78..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 217..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..245
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 293 AA; 32648 MW; 74904E44B67399F3 CRC64;
MPTSSSFKHR IKEQEDYIRD WTAHREEIAR ISQDLALIAR EINDVAGEID SVTSSGTAPS
TTLVDRVFDE SLNFQKIPPL VHSKTPEGNN GRSGDPRPQA AEPPDHLTIT RRRTWSRDEV
MGDNLLLSSV FQFSKKIRQS IDKTAGKIRI LFKDKDRNWD DIESKLRAES EVPIVKTSSM
EISSILQELK RVEKQLQAIN AMIDPDGTLE ALNNMGFPSA MLPSPPKQKS SPVNNHHSPG
QTPTLGQPEA RALHPAAVSA AAEFENAESE ADFSIHFNRV NPDGEEEDVT VHK
