ID   TRPD_SCHPO              Reviewed;         354 AA.
AC   O60122;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 133.
DE   RecName: Full=Anthranilate phosphoribosyltransferase;
DE            EC=2.4.2.18;
GN   Name=trp4; ORFNames=SPBC16G5.08;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate = 5-
CC         phospho-alpha-D-ribose 1-diphosphate + anthranilate;
CC         Xref=Rhea:RHEA:11768, ChEBI:CHEBI:16567, ChEBI:CHEBI:18277,
CC         ChEBI:CHEBI:33019, ChEBI:CHEBI:58017; EC=2.4.2.18;
CC   -!- PATHWAY: Amino-acid biosynthesis; L-tryptophan biosynthesis; L-
CC       tryptophan from chorismate: step 2/5.
CC   -!- SIMILARITY: Belongs to the anthranilate phosphoribosyltransferase
CC       family. {ECO:0000305}.
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DR   EMBL; CU329671; CAA19028.1; -; Genomic_DNA.
DR   PIR; T39600; T39600.
DR   RefSeq; NP_596757.1; NM_001023777.2.
DR   AlphaFoldDB; O60122; -.
DR   SMR; O60122; -.
DR   STRING; 4896.SPBC16G5.08.1; -.
DR   MaxQB; O60122; -.
DR   PaxDb; O60122; -.
DR   EnsemblFungi; SPBC16G5.08.1; SPBC16G5.08.1:pep; SPBC16G5.08.
DR   GeneID; 2540065; -.
DR   KEGG; spo:SPBC16G5.08; -.
DR   PomBase; SPBC16G5.08; trp4.
DR   VEuPathDB; FungiDB:SPBC16G5.08; -.
DR   eggNOG; KOG1438; Eukaryota.
DR   HOGENOM; CLU_034315_2_1_1; -.
DR   InParanoid; O60122; -.
DR   OMA; KCFNTLQ; -.
DR   PhylomeDB; O60122; -.
DR   UniPathway; UPA00035; UER00041.
DR   PRO; PR:O60122; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0004048; F:anthranilate phosphoribosyltransferase activity; ISO:PomBase.
DR   GO; GO:0000162; P:tryptophan biosynthetic process; EXP:PomBase.
DR   Gene3D; 3.40.1030.10; -; 1.
DR   HAMAP; MF_00211; TrpD; 1.
DR   InterPro; IPR005940; Anthranilate_Pribosyl_Tfrase.
DR   InterPro; IPR000312; Glycosyl_Trfase_fam3.
DR   InterPro; IPR035902; Nuc_phospho_transferase.
DR   PANTHER; PTHR43285; PTHR43285; 1.
DR   Pfam; PF00591; Glycos_transf_3; 1.
DR   SUPFAM; SSF52418; SSF52418; 1.
DR   TIGRFAMs; TIGR01245; trpD; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis;
KW   Glycosyltransferase; Reference proteome; Transferase;
KW   Tryptophan biosynthesis.
FT   CHAIN           1..354
FT                   /note="Anthranilate phosphoribosyltransferase"
FT                   /id="PRO_0000154527"
SQ   SEQUENCE   354 AA;  37556 MW;  1A2F404162AE89AC CRC64;
     MINTFNPEVR LAIHDLDKVG PAIPLENYEA ALRAILTGKA SPVETASFLA SLHLTKAEEV
     PDILMQTVQI LKSYSTPIAN IEMVSPRFVD IVGTGGDGHN TFNVSTASAI VAAGAGLWVC
     KHGNKASTSA SGSADLLMSF GCDLLNVTPK NIVSITEQCK FSFLFAPMCH PTLKNVAPIR
     KQLGLPTIFN LVGPLLNPIP TYARIIGVSK LSLGEVVAKT LLKLGAGRSL VVCGEEGLDE
     ISPAGPTHTW LVRDGTITHE VYTPESFHLQ SHPLSSVASG TPSANAILLE ELLSNMLHAN
     HPILDYVLMN TAALLHVAGM AESLREGVKI AQQSISSGAA LRELSNFSTI SQQP