ID   C17AA_PARBF             Reviewed;         618 AA.
AC   O05102;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Pesticidal crystal-like protein Cry17Aa;
DE   AltName: Full=Cbm72 mosquitocidal toxin;
DE   AltName: Full=Insecticidal toxin CryXVIIA(a);
GN   Name=cry17Aa; Synonyms=cbm72, cryXVIIA(a);
OS   Paraclostridium bifermentans (Clostridium bifermentans).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Paraclostridium.
OX   NCBI_TaxID=1490;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CH18 / subsp. Malaysia;
RX   PubMed=9602158; DOI=10.1016/s0378-1119(98)00122-x;
RA   Barloy F., Lecadet M.-M., Delecluse A.;
RT   "Cloning and sequencing of three new putative toxin genes from Clostridium
RT   bifermentans CH18.";
RL   Gene 211:293-299(1998).
CC   -!- FUNCTION: Not significantly toxic to mosquito larvae. May increase the
CC       toxicity of the Pesticidal crystal-like protein cry16Aa (Cbm71).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- DEVELOPMENTAL STAGE: Produced during sporulation.
CC   -!- SIMILARITY: Belongs to the delta endotoxin family. {ECO:0000305}.
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DR   EMBL; X99478; CAA67841.1; -; Genomic_DNA.
DR   AlphaFoldDB; O05102; -.
DR   SMR; O05102; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0001897; P:cytolysis by symbiont of host cells; IEA:InterPro.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.190.10; -; 1.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR038979; Pest_crys.
DR   InterPro; IPR005638; Pest_crys_C.
DR   InterPro; IPR005639; Pest_crys_N.
DR   InterPro; IPR036716; Pest_crys_N_sf.
DR   InterPro; IPR001178; Pest_cryst_cen_dom.
DR   InterPro; IPR036399; Pest_cryst_cen_dom_sf.
DR   PANTHER; PTHR37003; PTHR37003; 1.
DR   Pfam; PF03944; Endotoxin_C; 1.
DR   Pfam; PF00555; Endotoxin_M; 1.
DR   Pfam; PF03945; Endotoxin_N; 1.
DR   SUPFAM; SSF49785; SSF49785; 1.
DR   SUPFAM; SSF51096; SSF51096; 1.
DR   SUPFAM; SSF56849; SSF56849; 1.
PE   2: Evidence at transcript level;
KW   Secreted; Sporulation; Toxin; Virulence.
FT   CHAIN           1..618
FT                   /note="Pesticidal crystal-like protein Cry17Aa"
FT                   /id="PRO_0000174090"
SQ   SEQUENCE   618 AA;  71651 MW;  1B9C5251B9AD329D CRC64;
     MNNKKIEQNK IVEYNSNLDI QPRELNTLNG LVFTGATVSI ILPLIGTTAV VPVVGGVIGI
     IAALLPVIWP AGTSSNDNLF DAVMKDTEMI MDEKISEYVV NDAMTRLESL YNILDYYRLS
     KDFWEKNKDD PLAIAELKER FSKLHSQFIE SMAYFKRANY EVLLLPAYAN AANLHLLLLR
     EGLLLNKVID NFITEGLHYE EFKTKRSTYI AHCSTWYNKG LENIKNKTRD FNKINKYDAY
     MNLSVLDIIS LFLSYDPYQY DKATKLQTLT RTVFSDPLQR APRDLYISPK EETLFKNLKG
     LRAFFAEGDL VLTGFRNYFR NTYINDQIIE GDLFGYTTNN ERYKLFTDSK IYKVTVFIDN
     VALAIVKLIF HDTDNKEWDF SKTDITDINK YRKEEVYLNL LSNNEIQKEP SHYLYKMHHY
     GDNYNDSYLF QWIHQSISPE NYLFDKDKDD NYIITQIPAI KASELSNLGE LSLQAIKGPR
     FTGGNVILSS VSKIDNNDPL YGGTIKIPLL TAFNNTSKFK IRIYYAANHN YNHDYIGALL
     TINSQHVANF KFKQTFSGED YSNLSYNNYQ FDYLVQTVAF PQNTSDVTLN LQFFYDPKFL
     NDYKQIVIID KIEFIPEN