ID   C18BA_PAEPP             Reviewed;         675 AA.
AC   P57091;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Parasporal crystal protein Cry18Ba;
DE   AltName: Full=76 kDa crystal protein;
DE   AltName: Full=Crystaline parasporal protoxin;
DE   AltName: Full=Parasporal delta-endotoxin CryXVIIIB(a);
GN   Name=cry18Ba; Synonyms=cryXVIIIB(a);
OS   Paenibacillus popilliae (Bacillus popilliae).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=78057;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=BP3;
RA   Patel R., Yousten A.A., Rippere K.;
RT   "Detection of two new cry genes in Paenibacillus popilliae.";
RL   Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Binds to the brush border membrane vesicles of scarab larvae
CC       and damages the gut wall somehow to allow the vegetative cells of
CC       P.popilliae to enter the hemolymph. {ECO:0000250}.
CC   -!- DEVELOPMENTAL STAGE: The crystal protein is produced during sporulation
CC       and is accumulated both as an inclusion and as part of the spore coat.
CC   -!- SIMILARITY: Belongs to the delta endotoxin family. {ECO:0000305}.
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DR   EMBL; AF169250; AAF89667.1; -; Genomic_DNA.
DR   AlphaFoldDB; P57091; -.
DR   SMR; P57091; -.
DR   GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0001897; P:cytolysis by symbiont of host cells; IEA:InterPro.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.190.10; -; 1.
DR   Gene3D; 2.100.10.10; -; 2.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR005638; Pest_crys_C.
DR   InterPro; IPR005639; Pest_crys_N.
DR   InterPro; IPR036716; Pest_crys_N_sf.
DR   InterPro; IPR015214; Pest_cryst_cen_dom_Cry2A/18.
DR   InterPro; IPR036399; Pest_cryst_cen_dom_sf.
DR   Pfam; PF03944; Endotoxin_C; 1.
DR   Pfam; PF09131; Endotoxin_mid; 1.
DR   Pfam; PF03945; Endotoxin_N; 1.
DR   SUPFAM; SSF49785; SSF49785; 1.
DR   SUPFAM; SSF51096; SSF51096; 1.
DR   SUPFAM; SSF56849; SSF56849; 1.
PE   2: Evidence at transcript level;
KW   Sporulation; Toxin; Virulence.
FT   CHAIN           1..675
FT                   /note="Parasporal crystal protein Cry18Ba"
FT                   /id="PRO_0000174092"
SQ   SEQUENCE   675 AA;  75849 MW;  823B588B4AE81DF5 CRC64;
     MNNNGNALSR TALTPTNNKV ISGDLVTNGL PPIDNNIICS NGFMPINVTR KNPFRKRTTQ
     EFIREWTEWK ENSPSLFTAP IVGVVTSTLL EALKKQVQSR LLLLMTNLLF PNNSTSTMEE
     ILRATEQYVQ EQLDTVTWNR VSQELEGLKN NLRTFNDQID DFLQNRVEIS PTAMIDSINT
     MQQVFVNRLP QFQLSDYQLL LLPLFAQGAT LHLTFIRDII INAGEWNIPE AQLNTCKRYL
     KQYVAQYSNY ALSTYEGAFR ARFYPRATLE NMLQFKTFMT LNVLDLVSIW SLLKYMNLYI
     STSANLYNIG DNKVNEGEYS ISYWPFFNSY IQTKSNYVLS GVSGYAIRWY YLNTFFGEYI
     QDNLYNIIAS YVGGVNGPKI GVQLSTTELD KQIKQQARAG MPTGLDDLSF NCTLRNPTTV
     PYFACNFQEL TSSGTAGTGG FIRSDVFRSE DNICGLGTGY ASAWTSYPDY YITNISATVQ
     VDGINIDITP LCFGEDRAIT STHGVNKVIA VYNRKANIAG TNQNGTMIHQ APNDGTGFTV
     SPLHLASFTH PSEAHIQENY GNSGDSLRLT GPTTAITYML SGDGRTIYKL VLRVSGVITR
     ITAKVRGNSI GYLEYINTVD NNQGITDNGS KFQDFEFRPT ITIDAQTPIV LEFSATSNFD
     LMNLIFIPYY DTPIY