ID   C19L2_DANRE             Reviewed;         960 AA.
AC   Q3LSS0;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=CWF19-like protein 2;
GN   Name=cwf19l2;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RX   PubMed=15256591; DOI=10.1073/pnas.0403929101;
RA   Amsterdam A., Nissen R.M., Sun Z., Swindell E.C., Farrington S.,
RA   Hopkins N.;
RT   "Identification of 315 genes essential for early zebrafish development.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:12792-12797(2004).
CC   -!- SIMILARITY: Belongs to the CWF19 family. {ECO:0000305}.
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DR   EMBL; DQ181569; ABA19230.1; -; mRNA.
DR   AlphaFoldDB; Q3LSS0; -.
DR   SMR; Q3LSS0; -.
DR   STRING; 7955.ENSDARP00000108599; -.
DR   PaxDb; Q3LSS0; -.
DR   PRIDE; Q3LSS0; -.
DR   ZFIN; ZDB-GENE-050913-1; cwf19l2.
DR   eggNOG; KOG2477; Eukaryota.
DR   InParanoid; Q3LSS0; -.
DR   PRO; PR:Q3LSS0; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0071014; C:post-mRNA release spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   Gene3D; 3.30.428.10; -; 1.
DR   InterPro; IPR040194; Cwf19-like.
DR   InterPro; IPR006768; Cwf19-like_C_dom-1.
DR   InterPro; IPR006767; Cwf19-like_C_dom-2.
DR   InterPro; IPR036265; HIT-like_sf.
DR   PANTHER; PTHR12072; PTHR12072; 2.
DR   Pfam; PF04677; CwfJ_C_1; 1.
DR   Pfam; PF04676; CwfJ_C_2; 1.
DR   SUPFAM; SSF54197; SSF54197; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..960
FT                   /note="CWF19-like protein 2"
FT                   /id="PRO_0000315650"
FT   REGION          1..222
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          261..552
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          624..648
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          712..731
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..101
FT                   /evidence="ECO:0000255"
FT   COILED          163..279
FT                   /evidence="ECO:0000255"
FT   COILED          540..605
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        14..56
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        76..94
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        134..151
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        165..182
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        261..388
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        457..473
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        474..489
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        507..538
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        714..731
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   960 AA;  110570 MW;  6D9DC44FB40B4ECD CRC64;
     MAAYGVNFES ANSIKSRKES KREERERVIQ KAKEKFEKEE RRKAERKARG EDTWMLPDVD
     LRLQQIGEEH TVKTKKAKKE KKAKKSKKEK KKKAKKEKKD EGDASCDSSE DSEDEWVEAT
     LPSGGKDKSL EGEPEATPSS SSASNNQRDE WMTFDFLAMK TTSVADRRAQ KEAEKEAERQ
     KAQAIEQAGL HRLELNPYWK DGGSGLPPEE SSSTAVKKAG VVNDGGVSWL RKSYQRMKEQ
     ADREQRSLDS VVAERYGSME EFQKRLKEAE DAAYGERRDD EKERGRREEG KESWRRNDRE
     EGRERWRRDE EKDRWRRNDR DEGRERWRRE DGDEEKERWR KDGWRRGENE DRRRERSPNA
     ERERARSRDD LSSKFLKPSE DEEVSRGAGF KKGSSSNQSA AFRKPVDDVE MSREAGFKKG
     SSSNQNAAFR KPVDDEMSRG TAFKKGSSSN QSAAFRKPVD GDHDDDEMSR GAEFRKSSSS
     NQSAAFRKPI DNNNDGRGVA AAWRKSSAVQ DSETPTLQKH TEKSAALQED SKTTTTVSSS
     ESEEEEEEEL ILTDEEMNKL GAKIVKAEIM GNTALLEKLR AQMEAARRAK EKRAQIKDQS
     KRASKPAVSE KEVLLFRTDP SGRAWPVNAP SETLEPRGGR RKRKAIETHQ DGERVRYFDD
     DDGVDLREMV RREKMSSAED QNALYSRMAA KMMGRTDGDN YTLDDMFVSS AAQKERAGRD
     EERQRNKAVQ ETRRLAGRME KCPHCFDSAE LPKHLIIAVG TKVYLCLPNS VSLTEGHCLI
     VPVQHHTAAT GLDEDIWGEI QMFRRALVRM FESQELDCVF LETHMNPKRH LHMVYECVPM
     PRELGDMAPI YFKKAIMESD EEWAMNKKVV DLSKRDIRQA VPRGLPYFSV DFGLQGGFAH
     VIENEQKFPH YFGKEILGGM LDLEPRRWRK PIRENFDDQR KKVLKFAQWW KPFDCTKSDS