C1D_DANRE
ID C1D_DANRE Reviewed; 148 AA.
AC Q5XJ97;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=Nuclear nucleic acid-binding protein C1D;
GN Name=c1d; ORFNames=zgc:103509;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Ovary;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays a role in the recruitment of the exosome to pre-rRNA to
CC mediate the 3'-5' end processing of the 5.8S rRNA. {ECO:0000250}.
CC -!- SUBUNIT: Monomer and homodimer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q13901}. Cytoplasm
CC {ECO:0000250|UniProtKB:Q13901}. Nucleus, nucleolus
CC {ECO:0000250|UniProtKB:Q13901}.
CC -!- SIMILARITY: Belongs to the C1D family. {ECO:0000305}.
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DR EMBL; BC083407; AAH83407.1; -; mRNA.
DR RefSeq; NP_001007060.1; NM_001007059.1.
DR AlphaFoldDB; Q5XJ97; -.
DR SMR; Q5XJ97; -.
DR STRING; 7955.ENSDARP00000020042; -.
DR PaxDb; Q5XJ97; -.
DR GeneID; 474329; -.
DR KEGG; dre:474329; -.
DR CTD; 10438; -.
DR ZFIN; ZDB-GENE-041024-8; c1d.
DR eggNOG; KOG4835; Eukaryota.
DR InParanoid; Q5XJ97; -.
DR PhylomeDB; Q5XJ97; -.
DR Reactome; R-DRE-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR PRO; PR:Q5XJ97; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000178; C:exosome (RNase complex); IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0000460; P:maturation of 5.8S rRNA; IBA:GO_Central.
DR GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR InterPro; IPR011082; Exosome-assoc_fac/DNA_repair.
DR InterPro; IPR007146; Sas10/Utp3/C1D.
DR PANTHER; PTHR15341; PTHR15341; 1.
DR Pfam; PF04000; Sas10_Utp3; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Cytoplasm; DNA-binding; Nucleus; Reference proteome;
KW RNA-binding; rRNA processing.
FT CHAIN 1..148
FT /note="Nuclear nucleic acid-binding protein C1D"
FT /id="PRO_0000316304"
FT REGION 128..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 83..107
FT /evidence="ECO:0000255"
FT COMPBIAS 128..142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 148 AA; 17232 MW; 8E6BEDC50B36F8A4 CRC64;
MADDAAVEDY PTEIEDNLND FDSSLSSVQN MVQTLVSVSR SDRLLKLDPL EQAKLDLMSA
YALNSMFWMY LVTQGVNPKD HPIKQELERI RTYMNKVKEI TDRRKAAHID KEAASRFVRN
ALWDADDKKR KDKTEHQQKG KHTKFTWS