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C1D_DANRE
ID   C1D_DANRE               Reviewed;         148 AA.
AC   Q5XJ97;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Nuclear nucleic acid-binding protein C1D;
GN   Name=c1d; ORFNames=zgc:103509;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in the recruitment of the exosome to pre-rRNA to
CC       mediate the 3'-5' end processing of the 5.8S rRNA. {ECO:0000250}.
CC   -!- SUBUNIT: Monomer and homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q13901}. Cytoplasm
CC       {ECO:0000250|UniProtKB:Q13901}. Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q13901}.
CC   -!- SIMILARITY: Belongs to the C1D family. {ECO:0000305}.
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DR   EMBL; BC083407; AAH83407.1; -; mRNA.
DR   RefSeq; NP_001007060.1; NM_001007059.1.
DR   AlphaFoldDB; Q5XJ97; -.
DR   SMR; Q5XJ97; -.
DR   STRING; 7955.ENSDARP00000020042; -.
DR   PaxDb; Q5XJ97; -.
DR   GeneID; 474329; -.
DR   KEGG; dre:474329; -.
DR   CTD; 10438; -.
DR   ZFIN; ZDB-GENE-041024-8; c1d.
DR   eggNOG; KOG4835; Eukaryota.
DR   InParanoid; Q5XJ97; -.
DR   PhylomeDB; Q5XJ97; -.
DR   Reactome; R-DRE-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   PRO; PR:Q5XJ97; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000178; C:exosome (RNase complex); IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0000460; P:maturation of 5.8S rRNA; IBA:GO_Central.
DR   GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR   InterPro; IPR011082; Exosome-assoc_fac/DNA_repair.
DR   InterPro; IPR007146; Sas10/Utp3/C1D.
DR   PANTHER; PTHR15341; PTHR15341; 1.
DR   Pfam; PF04000; Sas10_Utp3; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasm; DNA-binding; Nucleus; Reference proteome;
KW   RNA-binding; rRNA processing.
FT   CHAIN           1..148
FT                   /note="Nuclear nucleic acid-binding protein C1D"
FT                   /id="PRO_0000316304"
FT   REGION          128..148
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          83..107
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        128..142
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   148 AA;  17232 MW;  8E6BEDC50B36F8A4 CRC64;
     MADDAAVEDY PTEIEDNLND FDSSLSSVQN MVQTLVSVSR SDRLLKLDPL EQAKLDLMSA
     YALNSMFWMY LVTQGVNPKD HPIKQELERI RTYMNKVKEI TDRRKAAHID KEAASRFVRN
     ALWDADDKKR KDKTEHQQKG KHTKFTWS
 
 
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