ID   C1L_VAR67               Reviewed;          66 AA.
AC   P0DTP8; P33797;
DT   16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT   16-OCT-2019, sequence version 1.
DT   29-SEP-2021, entry version 6.
DE   RecName: Full=Truncated interferon antagonist C1L;
GN   ORFNames=C1L;
OS   Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=587200;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8384129; DOI=10.1016/0014-5793(93)80041-r;
RA   Shchelkunov S.N., Blinov V.M., Sandakhchiev L.S.;
RT   "Genes of variola and vaccinia viruses necessary to overcome the host
RT   protective mechanisms.";
RL   FEBS Lett. 319:80-83(1993).
CC   -!- MISCELLANEOUS: This protein is homologous to the N-terminus of
CC       poxviridae interferon antagonist K1L. Presumably a premature stop codon
CC       mutated the gene in variola.
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DR   EMBL; X69198; CAA48962.1; -; Genomic_DNA.
DR   PIR; A36839; A36839.
DR   RefSeq; NP_042065.1; NC_001611.1.
DR   SMR; P0DTP8; -.
DR   GeneID; 1486576; -.
DR   KEGG; vg:1486576; -.
DR   Proteomes; UP000002060; Genome.
DR   Gene3D; 1.25.40.20; -; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   4: Predicted;
KW   ANK repeat; Reference proteome.
FT   CHAIN           1..66
FT                   /note="Truncated interferon antagonist C1L"
FT                   /id="PRO_0000067082"
FT   REPEAT          29..58
FT                   /note="ANK"
SQ   SEQUENCE   66 AA;  7465 MW;  EDCDB1CF8529732B CRC64;
     MDLSRINTRK SKQLKSFLSS KDTFKADVHG HSALYYAIAD NNMRLVCTLL NAGALKNLLE
     NEFPLH