ID   TRPO_PSEAE              Reviewed;         207 AA.
AC   P24908; Q9I796;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   04-MAY-2001, sequence version 2.
DT   03-AUG-2022, entry version 142.
DE   RecName: Full=Putative transcriptional regulator;
GN   OrderedLocusNames=PA0034;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-206.
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=3127651; DOI=10.1093/oxfordjournals.molbev.a040388;
RA   Hadero A., Crawford I.P.;
RT   "Nucleotide sequence of the genes for tryptophan synthase in Pseudomonas
RT   aeruginosa.";
RL   Mol. Biol. Evol. 3:191-204(1986).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
RN   [3]
RP   IDENTIFICATION OF PROTEIN, AND POSSIBLE DNA-BINDING REGION.
RX   PubMed=2314271; DOI=10.1016/0076-6879(90)83009-x;
RA   Henikoff S., Wallace J.C., Brown J.P.;
RT   "Finding protein similarities with nucleotide sequence databases.";
RL   Methods Enzymol. 183:111-132(1990).
CC   -!- FUNCTION: Probable transcriptional regulator.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=M15826; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; M15826; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AE004091; AAG03424.1; -; Genomic_DNA.
DR   PIR; F83640; F83640.
DR   RefSeq; NP_248724.1; NC_002516.2.
DR   RefSeq; WP_003111192.1; NZ_QZGE01000012.1.
DR   AlphaFoldDB; P24908; -.
DR   SMR; P24908; -.
DR   STRING; 287.DR97_2988; -.
DR   PaxDb; P24908; -.
DR   EnsemblBacteria; AAG03424; AAG03424; PA0034.
DR   GeneID; 879223; -.
DR   KEGG; pae:PA0034; -.
DR   PATRIC; fig|208964.12.peg.34; -.
DR   PseudoCAP; PA0034; -.
DR   HOGENOM; CLU_000445_90_1_6; -.
DR   InParanoid; P24908; -.
DR   OMA; LTMHDNE; -.
DR   PhylomeDB; P24908; -.
DR   BioCyc; PAER208964:G1FZ6-35-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   Pfam; PF00196; GerE; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   1: Evidence at protein level;
KW   DNA-binding; Phosphoprotein; Reference proteome; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..207
FT                   /note="Putative transcriptional regulator"
FT                   /id="PRO_0000081337"
FT   DOMAIN          3..118
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DOMAIN          140..205
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   DNA_BIND        155..174
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   MOD_RES         9
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   MOD_RES         53
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   CONFLICT        85..86
FT                   /note="PA -> RS (in Ref. 1)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        90..92
FT                   /note="PRC -> RR (in Ref. 1)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        121
FT                   /note="Y -> H (in Ref. 1)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   207 AA;  22860 MW;  230DC709085E87D8 CRC64;
     MSKVLIVDDH PAIRLAVRLL FERDGFTIVG EADNGAEALQ VARKKSPDLA ILDIGIPKID
     GLEVIARLKS LKLDTKVLVL TRQNPAQFAP RCLQAGAMGF VSKRENLSEL LLAAKAVLAG
     YIHFPTGALR SINQQSRDNE ARMLESLSDR EMTVLQYLAN GNTNKAIAQQ LFLSEKTVST
     YKSRIMLKLN AHSLAGLIDF ARRHELI