TRPP_CLOAB
ID TRPP_CLOAB Reviewed; 171 AA.
AC Q97D63;
DT 31-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2001, sequence version 1.
DT 25-MAY-2022, entry version 82.
DE RecName: Full=Probable tryptophan transport protein;
GN Name=trpP; OrderedLocusNames=CA_C3617;
OS Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710
OS / VKM B-1787).
OC Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=272562;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
RX PubMed=11466286; DOI=10.1128/jb.183.16.4823-4838.2001;
RA Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R.,
RA Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F.,
RA Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V.,
RA Smith D.R.;
RT "Genome sequence and comparative analysis of the solvent-producing
RT bacterium Clostridium acetobutylicum.";
RL J. Bacteriol. 183:4823-4838(2001).
CC -!- FUNCTION: Probably involved in tryptophan uptake. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the vitamin uptake transporter (VUT/ECF) (TC
CC 2.A.88) family. TrpP subfamily. {ECO:0000305}.
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DR EMBL; AE001437; AAK81540.1; -; Genomic_DNA.
DR PIR; A97344; A97344.
DR RefSeq; NP_350200.1; NC_003030.1.
DR RefSeq; WP_010966880.1; NC_003030.1.
DR AlphaFoldDB; Q97D63; -.
DR SMR; Q97D63; -.
DR STRING; 272562.CA_C3617; -.
DR EnsemblBacteria; AAK81540; AAK81540; CA_C3617.
DR GeneID; 45000115; -.
DR KEGG; cac:CA_C3617; -.
DR PATRIC; fig|272562.8.peg.3807; -.
DR eggNOG; ENOG5032SBU; Bacteria.
DR HOGENOM; CLU_126994_0_0_9; -.
DR OMA; DMMLTMM; -.
DR OrthoDB; 1750801at2; -.
DR Proteomes; UP000000814; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR InterPro; IPR031360; TrpP.
DR Pfam; PF17099; TrpP; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..171
FT /note="Probable tryptophan transport protein"
FT /id="PRO_0000109851"
FT TRANSMEM 9..31
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..80
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 107..129
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 139..161
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 171 AA; 18441 MW; CC9AAB476CEC8B0C CRC64;
MRMNLKKLII NSLFLAVGVV LNQITPPILF GMKPDFSLAM LFIIILLNDD YKTCISTGVV
AGLLAAAVTT FPGGQLPNII DRIVTTSLVF IALRPFKDKI NDKIHMIITT IVGTIISGSV
FLGSALIIVG LPASFKALFI TVVLPATIIN AIVGTIIFVA VKKSMRVVFR Q