TRPP_CLOPE
ID TRPP_CLOPE Reviewed; 182 AA.
AC P58725;
DT 31-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT 31-JAN-2002, sequence version 1.
DT 25-MAY-2022, entry version 83.
DE RecName: Full=Probable tryptophan transport protein;
GN Name=trpP; OrderedLocusNames=CPE1298;
OS Clostridium perfringens (strain 13 / Type A).
OC Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=195102;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=13 / Type A;
RX PubMed=11792842; DOI=10.1073/pnas.022493799;
RA Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A., Shiba T.,
RA Ogasawara N., Hattori M., Kuhara S., Hayashi H.;
RT "Complete genome sequence of Clostridium perfringens, an anaerobic flesh-
RT eater.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002).
CC -!- FUNCTION: Probably involved in tryptophan uptake. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the vitamin uptake transporter (VUT/ECF) (TC
CC 2.A.88) family. TrpP subfamily. {ECO:0000305}.
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DR EMBL; BA000016; BAB81004.1; -; Genomic_DNA.
DR RefSeq; WP_011010373.1; NC_003366.1.
DR AlphaFoldDB; P58725; -.
DR STRING; 195102.gene:10490561; -.
DR EnsemblBacteria; BAB81004; BAB81004; BAB81004.
DR KEGG; cpe:CPE1298; -.
DR HOGENOM; CLU_126994_0_0_9; -.
DR OMA; DMMLTMM; -.
DR Proteomes; UP000000818; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR InterPro; IPR031360; TrpP.
DR Pfam; PF17099; TrpP; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..182
FT /note="Probable tryptophan transport protein"
FT /id="PRO_0000109852"
FT TRANSMEM 10..32
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 119..141
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 146..168
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 182 AA; 19753 MW; E4F46C840E104041 CRC64;
MNVRNNTKLI TINALLLAIG VILHQITPVL GLPMQPDFAI TMLFIIIILN DNFKITMVSG
TLMGIFTAMT TKFPGGQLPN VVDKIFTALI VFLFIALIKK SNILGRLSVE KRNNILMAIV
LPLGTLVSGI LFLGTAKIIV GLPASFSILF LTVVVPSVAL NTVIGLVLYR IVEKSLRRAS
LL