ID   TRPR_PASMU              Reviewed;         102 AA.
AC   Q9CNU9;
DT   02-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 118.
DE   RecName: Full=Trp operon repressor homolog;
GN   Name=trpR; OrderedLocusNames=PM0325;
OS   Pasteurella multocida (strain Pm70).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Pasteurella.
OX   NCBI_TaxID=272843;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pm70;
RX   PubMed=11248100; DOI=10.1073/pnas.051634598;
RA   May B.J., Zhang Q., Li L.L., Paustian M.L., Whittam T.S., Kapur V.;
RT   "Complete genomic sequence of Pasteurella multocida Pm70.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:3460-3465(2001).
CC   -!- FUNCTION: This protein is an aporepressor. When complexed with L-
CC       tryptophan it binds the operator region of the trp operon and prevents
CC       the initiation of transcription (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TrpR family. {ECO:0000305}.
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DR   EMBL; AE004439; AAK02409.1; -; Genomic_DNA.
DR   RefSeq; WP_005751246.1; NC_002663.1.
DR   AlphaFoldDB; Q9CNU9; -.
DR   SMR; Q9CNU9; -.
DR   STRING; 747.DR93_1099; -.
DR   EnsemblBacteria; AAK02409; AAK02409; PM0325.
DR   KEGG; pmu:PM0325; -.
DR   HOGENOM; CLU_147939_0_0_6; -.
DR   OMA; GQMSQRE; -.
DR   Proteomes; UP000000809; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.1270.10; -; 1.
DR   HAMAP; MF_00475; Trp_repressor; 1.
DR   InterPro; IPR000831; Trp_repress.
DR   InterPro; IPR013335; Trp_repress_bac.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   InterPro; IPR038116; TrpR-like_sf.
DR   PANTHER; PTHR38025; PTHR38025; 1.
DR   Pfam; PF01371; Trp_repressor; 1.
DR   PIRSF; PIRSF003196; Trp_repressor; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   TIGRFAMs; TIGR01321; TrpR; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..102
FT                   /note="Trp operon repressor homolog"
FT                   /id="PRO_0000196511"
FT   DNA_BIND        59..82
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   102 AA;  11774 MW;  E25FE51480FACB18 CRC64;
     MYLSRNLEQW HAFVEMLRTA FAQGKEQEIL TLLLTPDERD SVGLRLQIVA QLLDKSVPQR
     EIQQNLNTSA ATITRGSNMI KTMPPEFMAW VKEQLDEQAK KD