TRS23_SCHPO
ID TRS23_SCHPO Reviewed; 132 AA.
AC O43041;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Transport protein particle subunit trs23;
DE Short=TRAPP subunit trs23;
GN Name=trs23; ORFNames=SPBC3B9.12;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- FUNCTION: TRAPP plays a key role in the late stages of endoplasmic
CC reticulum to Golgi traffic. {ECO:0000250}.
CC -!- SUBUNIT: Part of the multisubunit TRAPP (transport protein particle)
CC complex composed of bet3, bet5, trs20, trs23, trs31, trs33, trs65,
CC trs85, trs120 and trs130. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network {ECO:0000250}.
CC Endoplasmic reticulum {ECO:0000250}. Cytoplasm
CC {ECO:0000269|PubMed:16823372}. Nucleus {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the TRAPP small subunits family. TRAPPC4
CC subfamily. {ECO:0000305}.
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DR EMBL; CU329671; CAA17792.1; -; Genomic_DNA.
DR PIR; T40351; T40351.
DR RefSeq; NP_596670.1; NM_001022592.2.
DR AlphaFoldDB; O43041; -.
DR SMR; O43041; -.
DR BioGRID; 277492; 1.
DR STRING; 4896.SPBC3B9.12.1; -.
DR MaxQB; O43041; -.
DR PaxDb; O43041; -.
DR PRIDE; O43041; -.
DR EnsemblFungi; SPBC3B9.12.1; SPBC3B9.12.1:pep; SPBC3B9.12.
DR GeneID; 2540976; -.
DR KEGG; spo:SPBC3B9.12; -.
DR PomBase; SPBC3B9.12; trs23.
DR VEuPathDB; FungiDB:SPBC3B9.12; -.
DR eggNOG; KOG3369; Eukaryota.
DR HOGENOM; CLU_053380_2_2_1; -.
DR InParanoid; O43041; -.
DR OMA; YSMEMPI; -.
DR PhylomeDB; O43041; -.
DR Reactome; R-SPO-204005; COPII-mediated vesicle transport.
DR Reactome; R-SPO-8876198; RAB GEFs exchange GTP for GDP on RABs.
DR PRO; PR:O43041; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0030008; C:TRAPP complex; IBA:GO_Central.
DR GO; GO:1990070; C:TRAPPI protein complex; ISO:PomBase.
DR GO; GO:1990071; C:TRAPPII protein complex; ISO:PomBase.
DR GO; GO:1990072; C:TRAPPIII protein complex; ISO:PomBase.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IC:PomBase.
DR GO; GO:0006886; P:intracellular protein transport; NAS:PomBase.
DR GO; GO:0016236; P:macroautophagy; IC:PomBase.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR007233; TRAPPC.
DR PANTHER; PTHR23249; PTHR23249; 1.
DR Pfam; PF04099; Sybindin; 1.
DR SMART; SM01399; Sybindin; 1.
DR SUPFAM; SSF64356; SSF64356; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus;
KW Nucleus; Reference proteome; Transport.
FT CHAIN 1..132
FT /note="Transport protein particle subunit trs23"
FT /id="PRO_0000357022"
SQ SEQUENCE 132 AA; 14989 MW; F4FDA012A4E0AB80 CRC64;
MHALIIINRA GSLIFQREFG SSPTALTPNE YLVLAGTIHG VHAISTQISP LPGSSGIQLL
EAGTFNMHIL QTHTGMKFVL FTEKKTTNAR LQLQKFYELY SDYVLKNPFY TLEMPIKCQL
FDEQLKRYID SH
