ID   TRSX_VIBCL              Reviewed;         215 AA.
AC   Q79S39;
DT   23-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=HTH-type transcriptional regulator for conjugative element SXT;
GN   ORFNames=s087;
OS   Vibrio cholerae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=666;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=12107144; DOI=10.1128/jb.184.15.4259-4269.2002;
RA   Beaber J.W., Hochhut B., Waldor M.K.;
RT   "Genomic and functional analyses of SXT, an integrating antibiotic
RT   resistance gene transfer element derived from Vibrio cholerae.";
RL   J. Bacteriol. 184:4259-4269(2002).
CC   -!- FUNCTION: May control the expression of the integrase and inhibit
CC       excision of the mobile element SXT, and regulate the expression of
CC       other genes as well.
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DR   EMBL; AY055428; AAL59692.1; -; Genomic_DNA.
DR   RefSeq; WP_000854920.1; NZ_WYCS01000030.1.
DR   AlphaFoldDB; Q79S39; -.
DR   SMR; Q79S39; -.
DR   GeneID; 6803052; -.
DR   OMA; NGNCTIV; -.
DR   OrthoDB; 1933795at2; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00093; HTH_XRE; 1.
DR   CDD; cd06529; S24_LexA-like; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR039418; LexA-like.
DR   InterPro; IPR036286; LexA/Signal_pep-like_sf.
DR   InterPro; IPR015927; Peptidase_S24_S26A/B/C.
DR   Pfam; PF01381; HTH_3; 1.
DR   Pfam; PF00717; Peptidase_S24; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   SUPFAM; SSF51306; SSF51306; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   4: Predicted;
KW   DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..215
FT                   /note="HTH-type transcriptional regulator for conjugative
FT                   element SXT"
FT                   /id="PRO_0000149741"
FT   DOMAIN          8..61
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   DNA_BIND        19..38
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
SQ   SEQUENCE   215 AA;  23491 MW;  F536279FCC023262 CRC64;
     MKTLSERLNH ALQLTGVTQS ELARRIGIKQ QSISQICSGK SARSRYTMQI AEALRVNAHW
     LATGDGEIGL GVGNVEVGPD IKGRIPLINW VQAGDWTEIA EGFAHEDAEE WREVTGKAHE
     GCFALRVKGD SMENPSGKKS IPEGAVIVVD PELPYSSGSL VVARLDDSKE ATFKQLVIDG
     EQKYLKPLNP QYPAIPINGN CTIIGVVRQA IIDFW