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C1QT5_RAT
ID   C1QT5_RAT               Reviewed;         243 AA.
AC   Q5FVH0;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Complement C1q tumor necrosis factor-related protein 5;
DE   Flags: Precursor;
GN   Name=C1qtnf5; Synonyms=Ctrp5;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBUNIT: Homotrimer (via collagen-like domain). May form higher order
CC       oligomers by supercoiling of the trimers. May interact with ERFE (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
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DR   EMBL; BC089992; AAH89992.1; -; mRNA.
DR   RefSeq; NP_001012123.1; NM_001012123.1.
DR   RefSeq; XP_017451111.1; XM_017595622.1.
DR   AlphaFoldDB; Q5FVH0; -.
DR   SMR; Q5FVH0; -.
DR   IntAct; Q5FVH0; 1.
DR   STRING; 10116.ENSRNOP00000010127; -.
DR   PhosphoSitePlus; Q5FVH0; -.
DR   PaxDb; Q5FVH0; -.
DR   PRIDE; Q5FVH0; -.
DR   Ensembl; ENSRNOT00000010127; ENSRNOP00000010127; ENSRNOG00000007613.
DR   GeneID; 315598; -.
DR   KEGG; rno:315598; -.
DR   UCSC; RGD:1308802; rat.
DR   CTD; 114902; -.
DR   RGD; 1308802; C1qtnf5.
DR   eggNOG; ENOG502QUEA; Eukaryota.
DR   GeneTree; ENSGT00940000161353; -.
DR   HOGENOM; CLU_001074_0_2_1; -.
DR   InParanoid; Q5FVH0; -.
DR   OMA; YWQNSAV; -.
DR   OrthoDB; 1258047at2759; -.
DR   PhylomeDB; Q5FVH0; -.
DR   TreeFam; TF329591; -.
DR   PRO; PR:Q5FVH0; -.
DR   Proteomes; UP000002494; Chromosome 8.
DR   Bgee; ENSRNOG00000007613; Expressed in ovary and 19 other tissues.
DR   ExpressionAtlas; Q5FVH0; baseline and differential.
DR   Genevisible; Q5FVH0; RN.
DR   GO; GO:0016324; C:apical plasma membrane; ISO:RGD.
DR   GO; GO:0005923; C:bicellular tight junction; ISO:RGD.
DR   GO; GO:0042995; C:cell projection; ISO:RGD.
DR   GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR   GO; GO:0005576; C:extracellular region; ISO:RGD.
DR   GO; GO:0005615; C:extracellular space; ISO:RGD.
DR   GO; GO:0016328; C:lateral plasma membrane; ISO:RGD.
DR   GO; GO:0016020; C:membrane; ISO:RGD.
DR   GO; GO:0005886; C:plasma membrane; ISO:RGD.
DR   GO; GO:0032991; C:protein-containing complex; ISO:RGD.
DR   GO; GO:0030133; C:transport vesicle; ISO:RGD.
DR   GO; GO:0042802; F:identical protein binding; ISO:RGD.
DR   GO; GO:0048839; P:inner ear development; ISO:RGD.
DR   GO; GO:0009306; P:protein secretion; ISO:RGD.
DR   Gene3D; 2.60.120.40; -; 1.
DR   InterPro; IPR001073; C1q_dom.
DR   InterPro; IPR008160; Collagen.
DR   InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR   Pfam; PF00386; C1q; 1.
DR   Pfam; PF01391; Collagen; 2.
DR   PRINTS; PR00007; COMPLEMNTC1Q.
DR   SMART; SM00110; C1Q; 1.
DR   SUPFAM; SSF49842; SSF49842; 1.
DR   PROSITE; PS50871; C1Q; 1.
PE   2: Evidence at transcript level;
KW   Collagen; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000250"
FT   CHAIN           16..243
FT                   /note="Complement C1q tumor necrosis factor-related protein
FT                   5"
FT                   /id="PRO_0000003537"
FT   DOMAIN          30..95
FT                   /note="Collagen-like"
FT   DOMAIN          99..238
FT                   /note="C1q"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00368"
FT   REGION          15..124
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        46..60
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   243 AA;  25334 MW;  178AB5F39D52B041 CRC64;
     MRPLLALLLL GLASGSPPLD DNKIPSLCPG QPGLPGTPGH HGSQGLPGRD GRDGRDGAPG
     APGEKGEGGR PGLPGPRGEP GPRGEAGPVG AIGPAGECSV PPRSAFSAKR SESRVPPPAD
     TPLPFDRVLL NEQGHYDATT GKFTCQVPGV YYFAVHATVY RASLQFDLVK NGQSIASFFQ
     FFGGWPKPAS LSGGAMVRLE PEDQVWVQVG VGDYIGIYAS IKTDSTFSGF LVYSDWHSSP
     VFA
 
 
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