ID   C1_VAR67                Reviewed;         214 AA.
AC   P33859;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Protein C1;
GN   ORFNames=C1L, D14L, D18L;
OS   Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=587200;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=India-1967 / Isolate Ind3;
RX   PubMed=8384129; DOI=10.1016/0014-5793(93)80041-r;
RA   Shchelkunov S.N., Blinov V.M., Sandakhchiev L.S.;
RT   "Genes of variola and vaccinia viruses necessary to overcome the host
RT   protective mechanisms.";
RL   FEBS Lett. 319:80-83(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Congo-1965;
RA   Massung R.F., Loparev V.N., Knight J.C., Chizhikov V.E., Parsons J.M.,
RA   Totmenin A.V., Shchelkunov S.N., Esposito J.J.;
RL   Submitted (DEC-1994) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the orthopoxvirus C1 protein family.
CC       {ECO:0000305}.
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DR   EMBL; X69198; CAA48956.1; -; Genomic_DNA.
DR   EMBL; U18337; AAA69320.1; -; Genomic_DNA.
DR   PIR; E36838; E36838.
DR   RefSeq; NP_042059.1; NC_001611.1.
DR   SMR; P33859; -.
DR   GeneID; 1486395; -.
DR   KEGG; vg:1486395; -.
DR   Proteomes; UP000002060; Genome.
DR   InterPro; IPR008724; Orthopox_C1.
DR   InterPro; IPR022819; Poxvirus_Bcl-2-like.
DR   Pfam; PF06227; Poxvirus; 1.
DR   PIRSF; PIRSF003783; VAC_C1L; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..214
FT                   /note="Protein C1"
FT                   /id="PRO_0000099376"
SQ   SEQUENCE   214 AA;  25364 MW;  0363A14CD4F7DBEE CRC64;
     MIMSTDPNNI LMRYLKNLTD DKFKCIIHQS SDFLYLSDRD YTSITKETLV SEIVEEYPDD
     CNKILAIIFL VLDKDIDVDI DIETKLKPKP AVRYAILDKM TKDIKLTDLV RHYFRYIEQD
     IPLGPLFKKI DSYRIRAINK YSKELGLATE YFNKYGHLMF YTLPIPYNRF FCRNSIGFLA
     VLSPTIGHVK AFYKFIEYVS IDDRRKFKKE LMSK