ID   C2AIL_MOUSE             Reviewed;         116 AA.
AC   Q9D211; B1AU49;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=CDKN2AIP N-terminal-like protein;
DE   AltName: Full=CDKN2A-interacting protein N-terminal-like protein;
GN   Name=Cdkn2aipnl; Synonyms=D11Ertd497e; ORFNames=MNCb-1520;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Brain;
RA   Osada N., Kusuda J., Tanuma R., Ito A., Hirata M., Sugano S., Hashimoto K.;
RT   "isolation of full-length cDNA clones from mouse brain cDNA library made by
RT   oligo-capping method.";
RL   Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J, and NOD; TISSUE=Bone marrow, Spleen, and Thymus;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBUNIT: Interacts with XRN2; the interaction is direct.
CC       {ECO:0000250|UniProtKB:Q96HQ2}.
CC   -!- SIMILARITY: Belongs to the CARF family. {ECO:0000305}.
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DR   EMBL; AB041653; BAB93546.1; -; mRNA.
DR   EMBL; AK020751; BAB32201.1; -; mRNA.
DR   EMBL; AK150573; BAE29668.1; -; mRNA.
DR   EMBL; AK171740; BAE42643.1; -; mRNA.
DR   EMBL; AL669920; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC116362; AAI16363.1; -; mRNA.
DR   EMBL; BC116363; AAI16364.1; -; mRNA.
DR   CCDS; CCDS24663.1; -.
DR   RefSeq; NP_084252.1; NM_029976.3.
DR   AlphaFoldDB; Q9D211; -.
DR   SMR; Q9D211; -.
DR   BioGRID; 206699; 1.
DR   STRING; 10090.ENSMUSP00000099824; -.
DR   PhosphoSitePlus; Q9D211; -.
DR   EPD; Q9D211; -.
DR   MaxQB; Q9D211; -.
DR   PaxDb; Q9D211; -.
DR   PeptideAtlas; Q9D211; -.
DR   PRIDE; Q9D211; -.
DR   ProteomicsDB; 281710; -.
DR   Antibodypedia; 64397; 40 antibodies from 10 providers.
DR   Ensembl; ENSMUST00000102763; ENSMUSP00000099824; ENSMUSG00000020392.
DR   GeneID; 52626; -.
DR   KEGG; mmu:52626; -.
DR   UCSC; uc007ius.2; mouse.
DR   CTD; 91368; -.
DR   MGI; MGI:1261797; Cdkn2aipnl.
DR   VEuPathDB; HostDB:ENSMUSG00000020392; -.
DR   eggNOG; ENOG502S4FT; Eukaryota.
DR   GeneTree; ENSGT00940000157177; -.
DR   HOGENOM; CLU_148771_0_0_1; -.
DR   InParanoid; Q9D211; -.
DR   OMA; EDPHLDH; -.
DR   OrthoDB; 1524198at2759; -.
DR   PhylomeDB; Q9D211; -.
DR   TreeFam; TF333807; -.
DR   BioGRID-ORCS; 52626; 3 hits in 71 CRISPR screens.
DR   ChiTaRS; Cdkn2aipnl; mouse.
DR   PRO; PR:Q9D211; -.
DR   Proteomes; UP000000589; Chromosome 11.
DR   RNAct; Q9D211; protein.
DR   Bgee; ENSMUSG00000020392; Expressed in embryonic post-anal tail and 261 other tissues.
DR   ExpressionAtlas; Q9D211; baseline and differential.
DR   Genevisible; Q9D211; MM.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR   InterPro; IPR021859; XTBD.
DR   Pfam; PF11952; XTBD; 1.
DR   PROSITE; PS51827; XTBD; 1.
PE   3: Inferred from homology;
KW   Acetylation; Reference proteome.
FT   CHAIN           1..116
FT                   /note="CDKN2AIP N-terminal-like protein"
FT                   /id="PRO_0000325927"
FT   DOMAIN          24..116
FT                   /note="XRN2-binding (XTBD)"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01171"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96HQ2"
SQ   SEQUENCE   116 AA;  13209 MW;  DB76A3242AF6B227 CRC64;
     MVGGEASAAV EKLVSGVRQA ADFAEQFRSY SESEKQWKAR MEFILRHLPD YRDPPDGGGR
     LDQLLSLSMV WANHLFLGCS YNKDLLDKVM EMADGIEVED LPQFTTRSEL MRKHQS