C2C4D_MOUSE
ID C2C4D_MOUSE Reviewed; 341 AA.
AC P0CG09;
DT 15-JUN-2010, integrated into UniProtKB/Swiss-Prot.
DT 15-JUN-2010, sequence version 1.
DT 03-AUG-2022, entry version 61.
DE RecName: Full=C2 calcium-dependent domain-containing protein 4D;
GN Name=C2cd4d; Synonyms=Gm659;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
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DR EMBL; AC164562; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS50983.1; -.
DR RefSeq; NP_001129589.1; NM_001136117.1.
DR AlphaFoldDB; P0CG09; -.
DR SMR; P0CG09; -.
DR STRING; 10090.ENSMUSP00000128182; -.
DR iPTMnet; P0CG09; -.
DR PhosphoSitePlus; P0CG09; -.
DR PaxDb; P0CG09; -.
DR PRIDE; P0CG09; -.
DR ProteomicsDB; 281711; -.
DR Antibodypedia; 76708; 2 antibodies from 2 providers.
DR Ensembl; ENSMUST00000169433; ENSMUSP00000128182; ENSMUSG00000091648.
DR GeneID; 271944; -.
DR KEGG; mmu:271944; -.
DR UCSC; uc012ctl.1; mouse.
DR CTD; 100191040; -.
DR MGI; MGI:2685505; C2cd4d.
DR VEuPathDB; HostDB:ENSMUSG00000091648; -.
DR eggNOG; KOG4216; Eukaryota.
DR GeneTree; ENSGT00940000163537; -.
DR HOGENOM; CLU_051964_0_0_1; -.
DR InParanoid; P0CG09; -.
DR OMA; CAFLPES; -.
DR OrthoDB; 1256488at2759; -.
DR PhylomeDB; P0CG09; -.
DR TreeFam; TF330989; -.
DR BioGRID-ORCS; 271944; 6 hits in 74 CRISPR screens.
DR PRO; PR:P0CG09; -.
DR Proteomes; UP000000589; Chromosome 3.
DR RNAct; P0CG09; protein.
DR Bgee; ENSMUSG00000091648; Expressed in thymus and 47 other tissues.
DR Gene3D; 2.60.40.150; -; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR043549; C2C4C/C2C4D.
DR PANTHER; PTHR46291; PTHR46291; 2.
DR Pfam; PF00168; C2; 1.
DR SMART; SM00239; C2; 1.
DR SUPFAM; SSF49562; SSF49562; 1.
DR PROSITE; PS50004; C2; 1.
PE 4: Predicted;
KW Reference proteome.
FT CHAIN 1..341
FT /note="C2 calcium-dependent domain-containing protein 4D"
FT /id="PRO_0000394961"
FT DOMAIN 205..331
FT /note="C2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00041"
FT REGION 56..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 134..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 341 AA; 36865 MW; 4346EF3DD6A39BE9 CRC64;
MWLLEKAGYR VRTAEARALQ AHPSLVPKRQ ARGSPSRCNP NVLTPDRIPQ FFIPPRLRDP
RGAEGRVDRN PGGRNLPVAC SLPHLAGREG WAFLPESPHT RRRESLFHGP RGLAAGLAPA
QSRLHVSAPD LRLCRAPDSD TASSPDSSPC GSPHTPRPQS LSPDEASSAD TSPYAPRRAP
PLFHLDFLCC QLRPTKDSVL RLGPRGGQLR LSTEYQAGPG RLRLRLVSAE GLPRPRTRPG
SGGGGCCVIL RLQPRVRPGA QRSRVVQSSC NPIFNEDFFF EGLRPPDLAV RSLRAKVLDR
GAGLRRDVLL GECETPLIAL LPPLAGGLGP GSSLAPTHLS L