ID   TRX1_PSHV1              Reviewed;         486 AA.
AC   Q6UDJ3;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   23-FEB-2022, entry version 43.
DE   RecName: Full=Triplex capsid protein 1 {ECO:0000255|HAMAP-Rule:MF_04018};
GN   Name=TRX1 {ECO:0000255|HAMAP-Rule:MF_04018}; OrderedLocusNames=UL38;
OS   Psittacid herpesvirus 1 (isolate Amazon parrot/-/97-0001/1997) (PsHV-1)
OS   (Pacheco's disease virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Iltovirus.
OX   NCBI_TaxID=670426;
OH   NCBI_TaxID=152276; Amazona oratrix (yellow-headed parrot).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16873243; DOI=10.1128/jvi.00134-06;
RA   Thureen D.R., Keeler C.L. Jr.;
RT   "Psittacid herpesvirus 1 and infectious laryngotracheitis virus:
RT   Comparative genome sequence analysis of two avian alphaherpesviruses.";
RL   J. Virol. 80:7863-7872(2006).
CC   -!- FUNCTION: Structural component of the T=16 icosahedral capsid. The
CC       capsid is composed of pentamers and hexamers of major capsid
CC       protein/MCP, which are linked together by heterotrimers called
CC       triplexes. These triplexes are formed by a single molecule of triplex
CC       protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally,
CC       TRX1 is required for efficient transport of TRX2 to the nucleus, which
CC       is the site of capsid assembly. {ECO:0000255|HAMAP-Rule:MF_04018}.
CC   -!- SUBUNIT: Interacts with TRX2, MCP and capsid vertex component 2/CVC2.
CC       {ECO:0000255|HAMAP-Rule:MF_04018}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04018}. Host
CC       nucleus {ECO:0000255|HAMAP-Rule:MF_04018}.
CC   -!- SIMILARITY: Belongs to the herpesviridae TRX1 protein family.
CC       {ECO:0000255|HAMAP-Rule:MF_04018}.
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DR   EMBL; AY372243; AAQ73717.1; -; Genomic_DNA.
DR   RefSeq; NP_944411.1; NC_005264.1.
DR   SMR; Q6UDJ3; -.
DR   GeneID; 2657017; -.
DR   KEGG; vg:2657017; -.
DR   Proteomes; UP000006840; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0019069; P:viral capsid assembly; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_04018; HSV_TRX1; 1.
DR   InterPro; IPR004999; Herpes_1.
DR   Pfam; PF03327; Herpes_VP19C; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Host nucleus; Reference proteome; Virion.
FT   CHAIN           1..486
FT                   /note="Triplex capsid protein 1"
FT                   /id="PRO_0000406868"
SQ   SEQUENCE   486 AA;  52495 MW;  66204F2997B19762 CRC64;
     MANMKPNLTD LFRLRERADE GAARRENDRL LGLGSTVPQL LRPVWSGAPT VTGNIIGAIV
     NRGSAGTELL RTGPATNSGG GRMAAQQHAF GADDAAGVKA ALLGSIAPTA DALRAQQVLT
     TQVTVTDMCK PDVEGPGSLM LFFRGVRRLL IKLSAETMVR NDLINELETA FMILNRICGL
     PPVGTNGINN FEASLVSLNV LAAAAAPHYR NTCEVDALRT FVLAGGKDSK LNEKLTNLDL
     ILQASVESRN FPHSILFPAG ALTESVNSTN VACVKMLMNG SVELEGGLTR PCGSFRFPAC
     LFLDLDDTRQ CGVVPRGADR ADGLFYVYLL FLYSTETWHP SYEIYVAKSA LGEAGLQSML
     DEKFARRRVN NTVAAAPPAG NFYARGRQRE DGDWRCYIED AYRRASGNNA VNPLEQGARP
     TDLHISFAGV PDRNSATYAA FCQLGVSLGP WSSACRYTTV QRHGLGLKYV ELPGLSLKIG
     TWRACY