ID   TRX2_EHV1B              Reviewed;         314 AA.
AC   P28921;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   23-FEB-2022, entry version 76.
DE   RecName: Full=Triplex capsid protein 2 {ECO:0000255|HAMAP-Rule:MF_04019};
GN   Name=TRX2 {ECO:0000255|HAMAP-Rule:MF_04019}; OrderedLocusNames=43;
OS   Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX   NCBI_TaxID=31520;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=1318606; DOI=10.1016/0042-6822(92)90706-u;
RA   Telford E.A.R., Watson M.S., McBride K., Davison A.J.;
RT   "The DNA sequence of equine herpesvirus-1.";
RL   Virology 189:304-316(1992).
CC   -!- FUNCTION: Structural component of the T=16 icosahedral capsid. The
CC       capsid is composed of pentamers and hexamers of major capsid
CC       protein/MCP, which are linked together by heterotrimers called
CC       triplexes. These triplexes are formed by a single molecule of triplex
CC       protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally,
CC       TRX1 is required for efficient transport of TRX2 to the nucleus, which
CC       is the site of capsid assembly. {ECO:0000255|HAMAP-Rule:MF_04019}.
CC   -!- SUBUNIT: Interacts with TRX1 and major capisd protein/MCP.
CC       {ECO:0000255|HAMAP-Rule:MF_04019}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04019}. Host
CC       nucleus {ECO:0000255|HAMAP-Rule:MF_04019}.
CC   -!- SIMILARITY: Belongs to the herpesviridae TRX2 protein family.
CC       {ECO:0000255|HAMAP-Rule:MF_04019}.
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DR   EMBL; AY665713; AAT67301.1; -; Genomic_DNA.
DR   PIR; I36799; WZBED7.
DR   RefSeq; YP_053089.1; NC_001491.2.
DR   SMR; P28921; -.
DR   PRIDE; P28921; -.
DR   GeneID; 1487527; -.
DR   KEGG; vg:1487527; -.
DR   Proteomes; UP000001189; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-UniRule.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0019069; P:viral capsid assembly; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_04019; HSV_TRX2; 1.
DR   InterPro; IPR002690; Herpes_capsid_2.
DR   Pfam; PF01802; Herpes_V23; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Host nucleus; Reference proteome; Virion.
FT   CHAIN           1..314
FT                   /note="Triplex capsid protein 2"
FT                   /id="PRO_0000115726"
SQ   SEQUENCE   314 AA;  33842 MW;  BE2A56D4871ED3E6 CRC64;
     MASAAFEIDI LLPSDLSPAD LSALQKCEGK LVFLTALRRR VMLSSVTLSS YYVNGAPPDT
     LSLMAAFRRR FPAIIQRVLP NKMIAAALGV APLPPGAFIQ NTGPFDLCNG DSVCALPPIL
     DVEDKLRLGS VGEEILFPLT VPLAQARELI ARLVARAVQA LTPNAQAQRG AEVMFYNGRK
     YNVTPDLRHR DAVNGVARSL VLNMIFAMNE GSLVLLSLIP NLLTLGTQDG FVNAIIQMGS
     ATREVGQLVH QQPVPQPQDG ARRFCVYDAL MSWISVASRL GDVVGGKPLV RICTFEGQAT
     ISRGEKAPVI QTLL