ID   C2_ECTVM                Reviewed;         512 AA.
AC   Q8JLI4;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   23-FEB-2022, entry version 64.
DE   RecName: Full=Kelch repeat protein C2;
GN   OrderedLocusNames=EVM018;
OS   Ectromelia virus (strain Moscow) (ECTV) (Mousepox virus).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus.
OX   NCBI_TaxID=265874;
OH   NCBI_TaxID=10090; Mus musculus (Mouse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=14675635; DOI=10.1016/s0042-6822(03)00520-8;
RA   Chen N., Danila M.I., Feng Z., Buller R.M., Wang C., Han X.,
RA   Lefkowitz E.J., Upton C.;
RT   "The genomic sequence of Ectromelia virus, the causative agent of
RT   mousepox.";
RL   Virology 317:165-186(2003).
CC   -!- SIMILARITY: Belongs to the poxviruses Kelch family. {ECO:0000305}.
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DR   EMBL; AF012825; AAM92324.1; -; Genomic_DNA.
DR   RefSeq; NP_671536.1; NC_004105.1.
DR   SMR; Q8JLI4; -.
DR   GeneID; 951501; -.
DR   KEGG; vg:951501; -.
DR   Gene3D; 2.120.10.80; -; 1.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 2.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 3.
DR   SUPFAM; SSF117281; SSF117281; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   3: Inferred from homology;
KW   Kelch repeat; Repeat.
FT   CHAIN           1..512
FT                   /note="Kelch repeat protein C2"
FT                   /id="PRO_0000119163"
FT   DOMAIN          2..67
FT                   /note="BTB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT   DOMAIN          102..176
FT                   /note="BACK"
FT   REPEAT          216..261
FT                   /note="Kelch 1"
FT   REPEAT          262..307
FT                   /note="Kelch 2"
FT   REPEAT          309..354
FT                   /note="Kelch 3"
FT   REPEAT          356..403
FT                   /note="Kelch 4"
FT   REPEAT          405..449
FT                   /note="Kelch 5"
FT   REPEAT          452..498
FT                   /note="Kelch 6"
SQ   SEQUENCE   512 AA;  59037 MW;  608E7BEB260CEE78 CRC64;
     MESVIFSING EIIQVNKEII TASPYNLFKR IQDHHLKDEA IILNGINYHA FESLLDYMRW
     KKINITINNV EMILVAAIII DVPPVVDLCV KTMIHNINST NCIRMFNFSK RYGIKKLYNA
     SMSEIINNIT AVTSDPEFGK LSKDELTTIL SHENVNVNHE DVTAIILLKW IHKNPNDVDI
     INILHPKFMT NAMRNAIALL GLTISKSTKP VTRNGIKHNI VVIKNSDYIS TITHYSPRTE
     YWTIVGNTDR QFYNANVLHN CLYIIGGMIN NRHVYSVSRV DLKTKKWKTV TNMSSLKSEV
     STCVNNGKLY VIGGLEFSIS TAVAEYLKHG ASKWIRLPNL ITPRYSGASV FVNDDIYVMG
     GVYTTYEKYV VLNDVECFTK NRWIKKSPMP RHHSIVYAVE YDGDIYAITG ITHETRNYLY
     KYIVNEDKWI ELYMYFNHVG KMFVCSCGDY ILIIADAKYE YYPKSNTWNL LDTSTRNIEY
     YDMFTKDETP KCNVTHKSLP SFLSNCEKKF LQ