ID   TRXH_ORYSI              Reviewed;         122 AA.
AC   A2YIW7; O04743; Q42443; Q7EZX7;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Thioredoxin H-type;
DE            Short=Trx-H;
DE   AltName: Full=Phloem sap 13 kDa protein 1;
GN   Name=TRXH; ORFNames=OsI_024260;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Milyang 23; TISSUE=Seed;
RA   Lee M.C., Eun M.Y., Lee G.R.;
RT   "Isolation and characterization of thioredoxin h gene from rice.";
RL   Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND INDUCTION.
RC   STRAIN=cv. CO43; TISSUE=Leaf;
RX   PubMed=20034395; DOI=10.1186/1477-5956-7-47;
RA   Kandasamy S., Loganathan K., Muthuraj R., Duraisamy S., Seetharaman S.,
RA   Thiruvengadam R., Ponnusamy B., Ramasamy S.;
RT   "Understanding the molecular basis of plant growth promotional effect of
RT   Pseudomonas fluorescens on rice through protein profiling.";
RL   Proteome Sci. 7:47-47(2009).
CC   -!- FUNCTION: Participates in various redox reactions through the
CC       reversible oxidation of the active center dithiol to a disulfide. The H
CC       form is known to activate a number of cytosolic enzymes (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- INDUCTION: Up-regulated in the leaf sheaths of rice plants grown from
CC       seeds that were inoculated with the nonpathogenic P.fluorescens strain
CC       KH-1. {ECO:0000269|PubMed:20034395}.
CC   -!- MASS SPECTROMETRY: Mass=13319; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:20034395};
CC   -!- SIMILARITY: Belongs to the thioredoxin family. Plant H-type subfamily.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U92541; AAB51522.1; -; mRNA.
DR   EMBL; CM000132; EAZ03028.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2YIW7; -.
DR   SMR; A2YIW7; -.
DR   STRING; 39946.A2YIW7; -.
DR   PRIDE; A2YIW7; -.
DR   EnsemblPlants; BGIOSGA024701-TA; BGIOSGA024701-PA; BGIOSGA024701.
DR   Gramene; BGIOSGA024701-TA; BGIOSGA024701-PA; BGIOSGA024701.
DR   HOGENOM; CLU_090389_14_1_1; -.
DR   OMA; MKEWIKQ; -.
DR   Proteomes; UP000007015; Chromosome 7.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004857; F:enzyme inhibitor activity; IEA:EnsemblPlants.
DR   GO; GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IEA:EnsemblPlants.
DR   GO; GO:0015035; F:protein-disulfide reductase activity; IEA:InterPro.
DR   GO; GO:0010497; P:plasmodesmata-mediated intercellular transport; IEA:EnsemblPlants.
DR   GO; GO:0009409; P:response to cold; IEA:EnsemblPlants.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:EnsemblPlants.
DR   InterPro; IPR005746; Thioredoxin.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR017937; Thioredoxin_CS.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   PIRSF; PIRSF000077; Thioredoxin; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   PROSITE; PS00194; THIOREDOXIN_1; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm; Disulfide bond; Electron transport; Redox-active center;
KW   Reference proteome; Transport.
FT   CHAIN           1..122
FT                   /note="Thioredoxin H-type"
FT                   /id="PRO_0000303666"
FT   DOMAIN          2..118
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT   DISULFID        40..43
FT                   /note="Redox-active"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
SQ   SEQUENCE   122 AA;  13156 MW;  E595C3FDC0EE229E CRC64;
     MAAEEGVVIA CHNKDEFDAQ MTKAKEAGKV VIIDFTASWC GPCRFIAPVF AEYAKKFPGA
     VFLKVDVDEL KEVAEKYNVE AMPTFLFIKD GAEADKVVGA RKDDLQNTIV KHVGATAASA
     SA