ID   TRYP_PENMO              Reviewed;          32 AA.
AC   P35050;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Trypsin;
DE            EC=3.4.21.4;
DE   Flags: Fragment;
OS   Penaeus monodon (Giant tiger prawn).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC   Malacostraca; Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata;
OC   Penaeoidea; Penaeidae; Penaeus.
OX   NCBI_TaxID=6687;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Midgut;
RX   PubMed=1963309; DOI=10.1515/bchm3.1990.371.2.851;
RA   Lu P.J., Liu H.C., Tsai I.H.;
RT   "The midgut trypsins of shrimp (Penaeus monodon). High efficiency toward
RT   native protein substrates including collagens.";
RL   Biol. Chem. Hoppe-Seyler 371:851-859(1990).
CC   -!- FUNCTION: High efficiency toward native protein substrates including
CC       collagens.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.; EC=3.4.21.4;
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space.
CC   -!- SIMILARITY: Belongs to the peptidase S1 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00274}.
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DR   PIR; S11537; S11537.
DR   AlphaFoldDB; P35050; -.
DR   SMR; P35050; -.
DR   MEROPS; S01.111; -.
DR   GO; GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.10.10; -; 1.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   SUPFAM; SSF50494; SSF50494; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Hydrolase; Protease; Secreted; Serine protease.
FT   CHAIN           1..>32
FT                   /note="Trypsin"
FT                   /id="PRO_0000088719"
FT   DOMAIN          1..>32
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00274"
FT   NON_TER         32
SQ   SEQUENCE   32 AA;  3330 MW;  96A3A5D1F4B19182 CRC64;
     IVGGTAVTPG EFPYQLSFQD SIEGVESHFC GG