TRY_ARATH
ID TRY_ARATH Reviewed; 106 AA.
AC Q8GV05; Q9FGL7;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Transcription factor TRY;
DE AltName: Full=Protein TRIPTYCHON;
GN Name=TRY; OrderedLocusNames=At5g53200; ORFNames=MFH8.14;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, DEVELOPMENTAL STAGE, INDUCTION, AND
RP TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia; TISSUE=Root;
RX PubMed=12356720; DOI=10.1093/emboj/cdf524;
RA Schellmann S., Schnittger A., Kirik V., Wada T., Okada K., Beermann A.,
RA Thumfahrt J., Juergens G., Huelskamp M.;
RT "TRIPTYCHON and CAPRICE mediate lateral inhibition during trichome and root
RT hair patterning in Arabidopsis.";
RL EMBO J. 21:5036-5046(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Qu L.-J., Gu H.;
RT "The MYB transcription factor family in Arabidopsis: a genome-wide cloning
RT and expression pattern analysis.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP FUNCTION.
RX PubMed=10368181; DOI=10.2307/3870802;
RA Schnittger A., Folkers U., Schwab B., Juergens G., Huelskamp M.;
RT "Generation of a spacing pattern: the role of TRIPTYCHON in trichome
RT patterning in Arabidopsis.";
RL Plant Cell 11:1105-1116(1999).
RN [7]
RP INTERACTION WITH BHLH2.
RX PubMed=12917293; DOI=10.1242/dev.00681;
RA Zhang F., Gonzalez A., Zhao M., Payne C.T., Lloyd A.M.;
RT "A network of redundant bHLH proteins functions in all TTG1-dependent
RT pathways of Arabidopsis.";
RL Development 130:4859-4869(2003).
RN [8]
RP INTERACTION WITH GL3, AND SUBCELLULAR LOCATION.
RX PubMed=14561633; DOI=10.1242/dev.00812;
RA Esch J.J., Chen M., Sanders M., Hillestad M., Ndkium S., Idelkope B.,
RA Neizer J., Marks M.D.;
RT "A contradictory GLABRA3 allele helps define gene interactions controlling
RT trichome development in Arabidopsis.";
RL Development 130:5885-5894(2003).
RN [9]
RP GENE FAMILY.
RX PubMed=16463103; DOI=10.1007/s11103-005-2910-y;
RA Chen Y., Yang X., He K., Liu M., Li J., Gao Z., Lin Z., Zhang Y., Wang X.,
RA Qiu X., Shen Y., Zhang L., Deng X., Luo J., Deng X.-W., Chen Z., Gu H.,
RA Qu L.-J.;
RT "The MYB transcription factor superfamily of Arabidopsis: expression
RT analysis and phylogenetic comparison with the rice MYB family.";
RL Plant Mol. Biol. 60:107-124(2006).
CC -!- FUNCTION: Transcription factor. Involved in epidermal cell fate
CC specification. Negative regulator of trichome development, including
CC endoreplication, by lateral inhibition involving intercellular
CC interactions. Promotes the formation of hair developing cells
CC (trichoblasts) in H position in root epidermis, probably by inhibiting
CC non-hair cell (atrichoblasts) formation. {ECO:0000269|PubMed:10368181,
CC ECO:0000269|PubMed:12356720}.
CC -!- SUBUNIT: Interacts with GL3 and thus prevents GL1 GL3 interaction.
CC Interacts also with BHLH2. {ECO:0000269|PubMed:12917293,
CC ECO:0000269|PubMed:14561633}.
CC -!- INTERACTION:
CC Q8GV05; F4JI72: At4g03250; NbExp=3; IntAct=EBI-1545233, EBI-15192535;
CC Q8GV05; Q9FMC2: BZIP43; NbExp=3; IntAct=EBI-1545233, EBI-1237855;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:14561633}.
CC Note=Detected in trichome nucleus.
CC -!- TISSUE SPECIFICITY: Expressed in roots, leaves, siliques and
CC inflorescences. {ECO:0000269|PubMed:12356720}.
CC -!- DEVELOPMENTAL STAGE: Ubiquitous in young leaves. Later, restricted to
CC the leaf base in the trichome initiation zone. In mature leaves,
CC confined to trichome cells. {ECO:0000269|PubMed:12356720}.
CC -!- INDUCTION: Negative autoregulation. Repressed by CPC.
CC {ECO:0000269|PubMed:12356720}.
CC -!- MISCELLANEOUS: 'Triptychon' means 'triptych' in German. This protein
CC was called 'triptychon' because TRY regulates the branching of
CC trichomes in three branches.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB08423.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AY161286; AAN78321.1; -; mRNA.
DR EMBL; AY519523; AAS09993.1; -; mRNA.
DR EMBL; AB025622; BAB08423.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED96321.1; -; Genomic_DNA.
DR EMBL; BT024672; ABD57497.1; -; mRNA.
DR RefSeq; NP_200132.2; NM_124699.3.
DR AlphaFoldDB; Q8GV05; -.
DR SMR; Q8GV05; -.
DR BioGRID; 20646; 18.
DR IntAct; Q8GV05; 14.
DR STRING; 3702.AT5G53200.1; -.
DR PaxDb; Q8GV05; -.
DR PRIDE; Q8GV05; -.
DR EnsemblPlants; AT5G53200.1; AT5G53200.1; AT5G53200.
DR GeneID; 835401; -.
DR Gramene; AT5G53200.1; AT5G53200.1; AT5G53200.
DR KEGG; ath:AT5G53200; -.
DR Araport; AT5G53200; -.
DR TAIR; locus:2163766; AT5G53200.
DR eggNOG; ENOG502S4DP; Eukaryota.
DR HOGENOM; CLU_178021_1_0_1; -.
DR InParanoid; Q8GV05; -.
DR OMA; SSHKHTK; -.
DR OrthoDB; 1531077at2759; -.
DR PhylomeDB; Q8GV05; -.
DR PRO; PR:Q8GV05; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q8GV05; baseline and differential.
DR Genevisible; Q8GV05; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR GO; GO:0010154; P:fruit development; IMP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR GO; GO:1900032; P:regulation of trichome patterning; IMP:TAIR.
DR GO; GO:0010091; P:trichome branching; IMP:TAIR.
DR CDD; cd00167; SANT; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM00717; SANT; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS50090; MYB_LIKE; 1.
PE 1: Evidence at protein level;
KW Developmental protein; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..106
FT /note="Transcription factor TRY"
FT /id="PRO_0000285272"
FT DOMAIN 34..71
FT /note="Myb-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00133"
FT REGION 83..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 106 AA; 13006 MW; 2957DF51D3F86D86 CRC64;
MDNTDRRRRR KQHKIALHDS EEVSSIEWEF INMTEQEEDL IFRMYRLVGD RWDLIAGRVP
GRQPEEIERY WIMRNSEGFA DKRRQLHSSS HKHTKPHRPR FSIYPS
