ID   TRZA_GORRU              Reviewed;         477 AA.
AC   Q52725;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=S-triazine hydrolase;
DE            EC=3.8.1.-;
DE   AltName: Full=N-ethylammeline chlorohydrolase;
GN   Name=trzA;
OS   Gordonia rubripertincta (Rhodococcus corallinus).
OC   Bacteria; Actinobacteria; Corynebacteriales; Gordoniaceae; Gordonia.
OX   NCBI_TaxID=36822;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE.
RC   STRAIN=DSM 10347 / NRRL B-15444R;
RX   PubMed=7592318; DOI=10.1128/jb.177.20.5748-5755.1995;
RA   Shao Z.Q., Seffens W., Mulbry W., Behki R.M.;
RT   "Cloning and expression of the s-triazine hydrolase gene (trzA) from
RT   Rhodococcus corallinus and development of Rhodococcus recombinant strains
RT   capable of dealkylating and dechlorinating the herbicide atrazine.";
RL   J. Bacteriol. 177:5748-5755(1995).
CC   -!- FUNCTION: Hydrolytic deamination of the S-triazine substrate melamine.
CC   -!- PATHWAY: Xenobiotic degradation; melamine degradation.
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       ATZ/TRZ family. {ECO:0000305}.
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DR   EMBL; L16534; AAA90931.1; -; Genomic_DNA.
DR   PIR; T46666; T46666.
DR   AlphaFoldDB; Q52725; -.
DR   SMR; Q52725; -.
DR   BioCyc; MetaCyc:MON-13551; -.
DR   UniPathway; UPA00889; -.
DR   GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR   Gene3D; 2.30.40.10; -; 1.
DR   InterPro; IPR006680; Amidohydro-rel.
DR   InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   Pfam; PF01979; Amidohydro_1; 1.
DR   SUPFAM; SSF51338; SSF51338; 1.
DR   SUPFAM; SSF51556; SSF51556; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Hydrolase.
FT   INIT_MET        1
FT                   /note="Removed"
FT   CHAIN           2..477
FT                   /note="S-triazine hydrolase"
FT                   /id="PRO_0000122294"
FT   REGION          38..77
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          120..143
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   477 AA;  50858 MW;  3978763692F748FF CRC64;
     MTRIAITGGR VLTMDPERRV LEPGTVVVED QFIAQVGSPT TSTSAAPKSS TPPGWQCSPA
     SSTPTPTSHK SSSGVVHPMT ATSSNGCTTC SIPASLPTQT TTSESEHCCT APKPFVLASP
     LSSTTRTSDP TTSPAPGPPG SPFTDAGIRA IYARMYFDAP RAELEELVAT IHAKAPGAVR
     MDESASTDHV LADLDQLITR HDRTADGRIR VWPAPAIPFM VSEKGMKAAQ EIAASRTDGW
     TMHVSEDPIE ARVHSMNAPE YLHHLGCLDD RLLAAHCVHI DSRDIRLFRQ HDVKISTQPV
     SNSYLAAGIA PVPEMLAHGV TVGIGTDDAN CNDSVNLISD MKVLALIHRA AHRDASIITP
     EKIIEMATID GARCIGMADQ IGSLEAGKRA DIITLDLRHA QTTPAHDLAA TIVFQAYGNE
     VNDVLVNGSV VMRDRVLSFL PTPQEEKALY DDASERSAAM LARAGLTGTR TWQTLGS