C3H12_ORYSJ
ID C3H12_ORYSJ Reviewed; 439 AA.
AC Q5JLB5; A0A0N7KEA8; B7EN79; Q0JGL3; Q5JLB6;
DT 26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 2.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Zinc finger CCCH domain-containing protein 12;
DE Short=OsC3H12;
DE AltName: Full=Zinc finger CCCH domain-containing protein ZFN-like 2;
GN OrderedLocusNames=Os01g0917400, LOC_Os01g68860;
GN ORFNames=P0413C03.19-1, P0413C03.19-2;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP NOMENCLATURE.
RX PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL BMC Genomics 9:44-44(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q5JLB5-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q5JLB5-2; Sequence=VSP_013561;
CC -!- MISCELLANEOUS: [Isoform 2]: May be due to intron retention.
CC {ECO:0000305}.
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DR EMBL; AP003451; BAD87735.1; -; Genomic_DNA.
DR EMBL; AP003451; BAD87736.1; -; Genomic_DNA.
DR EMBL; AP008207; BAF07115.2; -; Genomic_DNA.
DR EMBL; AP014957; BAS75897.1; -; Genomic_DNA.
DR EMBL; AK098948; BAG93826.1; -; mRNA.
DR EMBL; AK112102; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015622340.1; XM_015766854.1. [Q5JLB5-1]
DR AlphaFoldDB; Q5JLB5; -.
DR STRING; 4530.OS01T0917400-01; -.
DR PaxDb; Q5JLB5; -.
DR PRIDE; Q5JLB5; -.
DR EnsemblPlants; Os01t0917400-01; Os01t0917400-01; Os01g0917400. [Q5JLB5-1]
DR GeneID; 4324354; -.
DR Gramene; Os01t0917400-01; Os01t0917400-01; Os01g0917400. [Q5JLB5-1]
DR KEGG; osa:4324354; -.
DR eggNOG; KOG1677; Eukaryota.
DR InParanoid; Q5JLB5; -.
DR OMA; ESECAYY; -.
DR OrthoDB; 657700at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR ExpressionAtlas; Q5JLB5; baseline and differential.
DR Genevisible; Q5JLB5; OS.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR Pfam; PF00642; zf-CCCH; 5.
DR SMART; SM00356; ZnF_C3H1; 5.
DR SUPFAM; SSF90229; SSF90229; 5.
DR PROSITE; PS50103; ZF_C3H1; 5.
PE 2: Evidence at transcript level;
KW Alternative splicing; DNA-binding; Metal-binding; Nucleus;
KW Reference proteome; Repeat; Zinc; Zinc-finger.
FT CHAIN 1..439
FT /note="Zinc finger CCCH domain-containing protein 12"
FT /id="PRO_0000213923"
FT ZN_FING 80..108
FT /note="C3H1-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 125..153
FT /note="C3H1-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 171..199
FT /note="C3H1-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 332..360
FT /note="C3H1-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 378..406
FT /note="C3H1-type 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 277..306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..39
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..117
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:12869764"
FT /id="VSP_013561"
FT CONFLICT 425
FT /note="V -> D (in Ref. 5; AK112102)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 439 AA; 47852 MW; 4D5EE9A051B57221 CRC64;
MDDAGRASAP AVVTVTASAA APTPPLPPPP PPPPPSQLPA TAAATDEPSH DPAALYGEGM
WQQMTMSGSG AMQPGPYPER SGEPDCTYYL RTGLCRFGMS CRFNHPQDRN LAIASARMKG
EYPERMGQPE CQYYLKTGTC KFGPTCKFHH PREKAGIAGR VQLNTLGYPL RPSEKECAYY
LKTGQCKYGN TCKFHHPELF NAMASSRGSP IYPSVHSSAT AGPPYTGTMA SWAFPRGSFI
PSPRWQNPSN YAPMIVPQGL VQVPSWNSYT GQMMPVSSSE SRLQSPGAQQ TYGTSQQVDA
SAGNQGMLSP YRSSSYPVPQ YALQRENVFP ERPDQPECQY YMKTGDCKFG AVCKFHHPRV
RSMPTPDCVL SPVGLPLRPG EELCKFYSRY GICKFGANCK FDHPTMAPPM GVYAYGSAST
NVPMVRRLLQ SPSASAYTS
