ID   TS57_MYCTO              Reviewed;         444 AA.
AC   P9WKH6; L0TFA3; Q10621;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 41.
DE   RecName: Full=Transposase for insertion sequence element IS1557;
GN   OrderedLocusNames=MT1353;
GN   and
GN   OrderedLocusNames=MT3905;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SIMILARITY: Belongs to the transposase 12 family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK45615.1; -; Genomic_DNA.
DR   EMBL; AE000516; AAK48271.1; -; Genomic_DNA.
DR   PIR; E70775; E70775.
DR   RefSeq; WP_003900758.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WKH6; -.
DR   SMR; P9WKH6; -.
DR   EnsemblBacteria; AAK45615; AAK45615; MT1353.
DR   EnsemblBacteria; AAK48271; AAK48271; MT3905.
DR   KEGG; mtc:MT1353; -.
DR   KEGG; mtc:MT3905; -.
DR   PATRIC; fig|83331.31.peg.4202; -.
DR   HOGENOM; CLU_041900_0_1_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR   InterPro; IPR002560; Transposase_DDE.
DR   InterPro; IPR032877; Transposase_HTH.
DR   InterPro; IPR029261; Transposase_Znf.
DR   Pfam; PF01610; DDE_Tnp_ISL3; 1.
DR   Pfam; PF13542; HTH_Tnp_ISL3; 1.
DR   Pfam; PF14690; zf-ISL3; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Transposable element; Transposition.
FT   CHAIN           1..444
FT                   /note="Transposase for insertion sequence element IS1557"
FT                   /id="PRO_0000427652"
FT   REGION          273..292
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VARIANT         433
FT                   /note="L -> R (in MT1353)"
SQ   SEQUENCE   444 AA;  50186 MW;  A580EC7A0630367F CRC64;
     MRNVRLFRAL LGVDKRTVIE DIEFEEDDAG DGARVIARVR PRSAVLRRCG RCGRKASWYD
     RGAGLRQWRS LDWGTVEVFL EAEAPRVNCP THGPTVVAVP WARHHAGHTY AFDDTVAWLA
     VACSKTAVCE LMRIAWRTVG AIVARVWADT EKRIDRFANL RRIGIDEISY KRHHRYLTVV
     VDHDSGRLVW AAPGHDKATL GLFFDALGAE RAAQITHVSA DAADWIADVV TERCPDAIQC
     ADPFHVVAWA TEALDVERRR AWNDARAIAR TEPKWGRGRP GKNAAPRPGR ERARRLKGAR
     YALWKNPEDL TERQSAKLAW IAKTDPRLYR AYLLKESLRH VFSVKGEEGK QALDRWISWA
     QRCRIPVFVE LAARIKRHRV AIDAALDHGL SQGLIESTNT KIRLLTRIAF GFRSPQALIA
     LAMLTLAGHR PTLPGRHNHP QISQ