C3H15_ARATH
ID C3H15_ARATH Reviewed; 308 AA.
AC Q9C9F5; Q1PFF3;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Zinc finger CCCH domain-containing protein 15;
DE Short=AtC3H15;
GN OrderedLocusNames=At1g68200; ORFNames=T22E19.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RA Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NOMENCLATURE.
RX PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL BMC Genomics 9:44-44(2008).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9C9F5-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9C9F5-2; Sequence=VSP_037129;
CC -!- MISCELLANEOUS: [Isoform 2]: May be due to a competing acceptor splice
CC site. {ECO:0000305}.
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DR EMBL; AC016447; AAG52611.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34763.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34764.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM59412.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM59413.1; -; Genomic_DNA.
DR EMBL; DQ446410; ABE65754.1; -; mRNA.
DR EMBL; DQ056514; AAY78670.1; -; mRNA.
DR EMBL; BT026077; ABG48433.1; -; mRNA.
DR PIR; D96705; D96705.
DR RefSeq; NP_001077792.1; NM_001084323.1. [Q9C9F5-2]
DR RefSeq; NP_001319344.1; NM_001334354.1. [Q9C9F5-1]
DR RefSeq; NP_001319345.1; NM_001334355.1. [Q9C9F5-2]
DR RefSeq; NP_176987.1; NM_105491.2. [Q9C9F5-1]
DR AlphaFoldDB; Q9C9F5; -.
DR SMR; Q9C9F5; -.
DR STRING; 3702.AT1G68200.1; -.
DR PaxDb; Q9C9F5; -.
DR PRIDE; Q9C9F5; -.
DR EnsemblPlants; AT1G68200.1; AT1G68200.1; AT1G68200. [Q9C9F5-1]
DR EnsemblPlants; AT1G68200.2; AT1G68200.2; AT1G68200. [Q9C9F5-2]
DR EnsemblPlants; AT1G68200.5; AT1G68200.5; AT1G68200. [Q9C9F5-1]
DR EnsemblPlants; AT1G68200.6; AT1G68200.6; AT1G68200. [Q9C9F5-2]
DR GeneID; 843149; -.
DR Gramene; AT1G68200.1; AT1G68200.1; AT1G68200. [Q9C9F5-1]
DR Gramene; AT1G68200.2; AT1G68200.2; AT1G68200. [Q9C9F5-2]
DR Gramene; AT1G68200.5; AT1G68200.5; AT1G68200. [Q9C9F5-1]
DR Gramene; AT1G68200.6; AT1G68200.6; AT1G68200. [Q9C9F5-2]
DR KEGG; ath:AT1G68200; -.
DR Araport; AT1G68200; -.
DR TAIR; locus:2199352; AT1G68200.
DR eggNOG; KOG1677; Eukaryota.
DR HOGENOM; CLU_050602_0_0_1; -.
DR InParanoid; Q9C9F5; -.
DR OMA; YNESEPD; -.
DR PhylomeDB; Q9C9F5; -.
DR PRO; PR:Q9C9F5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C9F5; baseline and differential.
DR Genevisible; Q9C9F5; AT.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR045877; ZFP36-like.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR PANTHER; PTHR12547; PTHR12547; 1.
DR Pfam; PF00642; zf-CCCH; 1.
DR SMART; SM00356; ZnF_C3H1; 2.
DR SUPFAM; SSF90229; SSF90229; 2.
DR PROSITE; PS50103; ZF_C3H1; 2.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; DNA-binding; Metal-binding;
KW Reference proteome; Repeat; Zinc; Zinc-finger.
FT CHAIN 1..308
FT /note="Zinc finger CCCH domain-containing protein 15"
FT /id="PRO_0000371974"
FT ZN_FING 222..250
FT /note="C3H1-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 260..288
FT /note="C3H1-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 110..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 56..91
FT /evidence="ECO:0000255"
FT COMPBIAS 122..138
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..170
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 196
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:17147637"
FT /id="VSP_037129"
SQ SEQUENCE 308 AA; 34227 MW; 296F894DD1B0813A CRC64;
MENKIAPFSY SGSSAGNSSS GGVVSSSLYS DQLYKSTRNI MQQRQDMVNR EALCYTRLHE
ASLEAEALRL ENTELRSMNL RLKNELNSLI RSSIQNRFDH RSPLRMLSNL SIGGNDADEV
ENQNRTVNRD DVNDKSPTSV MENEDLNRSS LPKSISVRSN GYSKASQGGG GAAAQSGKPR
GTVTKPGTCG QVSTTQKVYV RGGGKKEDQE EEIEVEVYNQ GMTKTELCNK WQETGTCPYG
DHCQFAHGIK ELRPVIRHPR YKTEVCRMVL AGDNCPYGHR CHFRHSLSEQ EKLVAAGFKP
KSSLKLIT
