C3H1_ARATH
ID C3H1_ARATH Reviewed; 343 AA.
AC Q8GX84; Q9LNI9;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 2.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Zinc finger CCCH domain-containing protein 1;
DE Short=AtC3H1;
GN OrderedLocusNames=At1g01350; ORFNames=F6F3.14;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NOMENCLATURE.
RX PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL BMC Genomics 9:44-44(2008).
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF97335.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC023628; AAF97335.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE27275.1; -; Genomic_DNA.
DR EMBL; AK118376; BAC42988.1; -; mRNA.
DR PIR; G86143; G86143.
DR RefSeq; NP_171642.2; NM_100017.3.
DR AlphaFoldDB; Q8GX84; -.
DR BioGRID; 24202; 1.
DR IntAct; Q8GX84; 1.
DR STRING; 3702.AT1G01350.1; -.
DR iPTMnet; Q8GX84; -.
DR PaxDb; Q8GX84; -.
DR PRIDE; Q8GX84; -.
DR ProteomicsDB; 239087; -.
DR EnsemblPlants; AT1G01350.1; AT1G01350.1; AT1G01350.
DR GeneID; 838964; -.
DR Gramene; AT1G01350.1; AT1G01350.1; AT1G01350.
DR KEGG; ath:AT1G01350; -.
DR Araport; AT1G01350; -.
DR TAIR; locus:2035377; AT1G01350.
DR eggNOG; KOG1813; Eukaryota.
DR HOGENOM; CLU_050460_1_2_1; -.
DR InParanoid; Q8GX84; -.
DR OMA; ICRDSFK; -.
DR OrthoDB; 1420266at2759; -.
DR PhylomeDB; Q8GX84; -.
DR PRO; PR:Q8GX84; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8GX84; baseline and differential.
DR Genevisible; Q8GX84; AT.
DR GO; GO:0005684; C:U2-type spliceosomal complex; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0034247; P:snoRNA splicing; IBA:GO_Central.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR039971; CWC24-like.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR12930; PTHR12930; 1.
DR Pfam; PF00642; zf-CCCH; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00356; ZnF_C3H1; 1.
DR SUPFAM; SSF90229; SSF90229; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..343
FT /note="Zinc finger CCCH domain-containing protein 1"
FT /id="PRO_0000371963"
FT ZN_FING 200..228
FT /note="C3H1-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 277..315
FT /note="RING-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT REGION 1..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 249..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..35
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..58
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 232
FT /note="P -> S (in Ref. 3; BAC42988)"
FT /evidence="ECO:0000305"
FT CONFLICT 304
FT /note="H -> R (in Ref. 3; BAC42988)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 343 AA; 38710 MW; 86E6DE6EDF1A3E04 CRC64;
MSDSGEPKPS QQEEPLPQPA AQETQSQQVC TFFKKPTKSK NIRKRTIDAD EEDGDSKSES
SILQNLKKVA KPDSKLYFSS GPSKSSTTTS GAPERSVFHY DSSKEIQVQN DSGATATLET
ETDFNQDARA IRERVLKKAD EALKGNKKKA SDEKLYKGIH GYTDHKAGFR REQTISSEKA
GGSHGPLRAS AHIRVSARFD YQPDICKDYK ETGYCGYGDS CKFLHDRGDY KPGWQIEKEW
EEAEKVRKRN KAMGVEDEDD EADKDSDEDE NALPFACFIC REPFVDPVVT KCKHYFCEHC
ALKHHTKNKK CFVCNQPTMG IFNAAHEIKK RMAEERSKAE QGL
