C3H23_ARATH
ID C3H23_ARATH Reviewed; 315 AA.
AC O82307; P93029; Q8LA97;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Zinc finger CCCH domain-containing protein 23;
DE Short=AtC3H23;
DE AltName: Full=Protein ATCTH;
GN OrderedLocusNames=At2g25900; ORFNames=F17H15.7;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 6-315.
RC STRAIN=cv. Columbia;
RA Fett-Neto A.G., McClung C.R.;
RT "A cDNA encoding a putative Cys3His zinc finger protein in Arabidopsis
RT thaliana.";
RL (er) Plant Gene Register PGR97-031(1997).
RN [7]
RP NOMENCLATURE.
RX PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL BMC Genomics 9:44-44(2008).
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB68046.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=AAB68046.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AC005395; AAC42256.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07769.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07770.1; -; Genomic_DNA.
DR EMBL; AF370590; AAK43909.1; -; mRNA.
DR EMBL; AF375403; AAK52987.1; -; mRNA.
DR EMBL; AY129468; AAM91054.1; -; mRNA.
DR EMBL; AK117272; BAC41945.1; -; mRNA.
DR EMBL; AY087957; AAM65505.1; -; mRNA.
DR EMBL; U81238; AAB68046.1; ALT_SEQ; mRNA.
DR PIR; B84654; B84654.
DR RefSeq; NP_001189604.1; NM_001202675.1.
DR RefSeq; NP_180161.1; NM_128150.5.
DR AlphaFoldDB; O82307; -.
DR BioGRID; 2483; 13.
DR IntAct; O82307; 12.
DR STRING; 3702.AT2G25900.1; -.
DR PaxDb; O82307; -.
DR PRIDE; O82307; -.
DR ProteomicsDB; 240515; -.
DR EnsemblPlants; AT2G25900.1; AT2G25900.1; AT2G25900.
DR EnsemblPlants; AT2G25900.2; AT2G25900.2; AT2G25900.
DR GeneID; 817131; -.
DR Gramene; AT2G25900.1; AT2G25900.1; AT2G25900.
DR Gramene; AT2G25900.2; AT2G25900.2; AT2G25900.
DR KEGG; ath:AT2G25900; -.
DR Araport; AT2G25900; -.
DR TAIR; locus:2043565; AT2G25900.
DR eggNOG; KOG1595; Eukaryota.
DR HOGENOM; CLU_044407_0_0_1; -.
DR InParanoid; O82307; -.
DR OMA; YRTHLCK; -.
DR OrthoDB; 1188286at2759; -.
DR PhylomeDB; O82307; -.
DR PRO; PR:O82307; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O82307; baseline and differential.
DR Genevisible; O82307; AT.
DR GO; GO:0005737; C:cytoplasm; IDA:TAIR.
DR GO; GO:0003677; F:DNA binding; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IDA:TAIR.
DR GO; GO:0003727; F:single-stranded RNA binding; IDA:TAIR.
DR GO; GO:0061157; P:mRNA destabilization; IDA:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR045234; Unkempt-like.
DR InterPro; IPR041367; Znf-CCCH_4.
DR InterPro; IPR000571; Znf_CCCH.
DR PANTHER; PTHR14493; PTHR14493; 1.
DR Pfam; PF18044; zf-CCCH_4; 1.
DR SMART; SM00356; ZnF_C3H1; 2.
DR PROSITE; PS50103; ZF_C3H1; 2.
PE 2: Evidence at transcript level;
KW DNA-binding; Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger.
FT CHAIN 1..315
FT /note="Zinc finger CCCH domain-containing protein 23"
FT /id="PRO_0000371982"
FT ZN_FING 131..157
FT /note="C3H1-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 165..189
FT /note="C3H1-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 148
FT /note="D -> H (in Ref. 5; AAM65505)"
FT /evidence="ECO:0000305"
FT CONFLICT 258
FT /note="R -> G (in Ref. 5; AAM65505)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 315 AA; 35465 MW; 320F0157B4C432FB CRC64;
MMIGENKNRP HPTIHIPQWD QINDPTATIS SPFSSVNLNS VNDYPHSPSP YLDSFASLFR
YLPSNELTND SDSSSGDESS PLTDSFSSDE FRIYEFKIRR CARGRSHDWT ECPFAHPGEK
ARRRDPRKFH YSGTACPEFR KGSCRRGDSC EFSHGVFECW LHPSRYRTQP CKDGTSCRRR
ICFFAHTTEQ LRVLPCSLDP DLGFFSGLAT SPTSILVSPS FSPPSESPPL SPSTGELIAS
MRKMQLNGGG CSWSSPMRSA VRLPFSSSLR PIQAATWPRI REFEIEEAPA MEFVESGKEL
RAEMYARLSR ENSLG
