C3H25_ARATH
ID C3H25_ARATH Reviewed; 483 AA.
AC Q9ZW36;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Zinc finger CCCH domain-containing protein 25;
DE Short=AtC3H25;
GN OrderedLocusNames=At2g29580; ORFNames=F16P2.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NOMENCLATURE.
RX PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL BMC Genomics 9:44-44(2008).
CC -!- INTERACTION:
CC Q9ZW36; Q9SY59: NFXL1; NbExp=3; IntAct=EBI-15195245, EBI-15201298;
CC Q9ZW36; O82277: TCP10; NbExp=3; IntAct=EBI-15195245, EBI-3133327;
CC Q9ZW36; Q9S7W5: TCP13; NbExp=3; IntAct=EBI-15195245, EBI-4424877;
CC Q9ZW36; Q84MB2: TIFY8; NbExp=3; IntAct=EBI-15195245, EBI-4426557;
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DR EMBL; AC004561; AAC95181.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08275.1; -; Genomic_DNA.
DR EMBL; AF428354; AAL16284.1; -; mRNA.
DR EMBL; BT002621; AAO11537.1; -; mRNA.
DR PIR; A84698; A84698.
DR RefSeq; NP_180518.1; NM_128511.2.
DR AlphaFoldDB; Q9ZW36; -.
DR SMR; Q9ZW36; -.
DR BioGRID; 2857; 47.
DR IntAct; Q9ZW36; 46.
DR STRING; 3702.AT2G29580.1; -.
DR iPTMnet; Q9ZW36; -.
DR PaxDb; Q9ZW36; -.
DR PRIDE; Q9ZW36; -.
DR ProteomicsDB; 240256; -.
DR EnsemblPlants; AT2G29580.1; AT2G29580.1; AT2G29580.
DR GeneID; 817507; -.
DR Gramene; AT2G29580.1; AT2G29580.1; AT2G29580.
DR KEGG; ath:AT2G29580; -.
DR Araport; AT2G29580; -.
DR TAIR; locus:2043157; AT2G29580.
DR eggNOG; KOG0153; Eukaryota.
DR HOGENOM; CLU_027112_2_0_1; -.
DR InParanoid; Q9ZW36; -.
DR OMA; QGQHYPY; -.
DR OrthoDB; 1272857at2759; -.
DR PhylomeDB; Q9ZW36; -.
DR PRO; PR:Q9ZW36; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZW36; baseline and differential.
DR Genevisible; Q9ZW36; AT.
DR GO; GO:0000974; C:Prp19 complex; IBA:GO_Central.
DR GO; GO:0071006; C:U2-type catalytic step 1 spliceosome; IBA:GO_Central.
DR GO; GO:0071007; C:U2-type catalytic step 2 spliceosome; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0036002; F:pre-mRNA binding; IBA:GO_Central.
DR GO; GO:0017070; F:U6 snRNA binding; IBA:GO_Central.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR039171; Cwc2/Slt11.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR032297; Torus.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR PANTHER; PTHR14089; PTHR14089; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF16131; Torus; 1.
DR SMART; SM00360; RRM; 1.
DR SMART; SM00356; ZnF_C3H1; 1.
DR SUPFAM; SSF54928; SSF54928; 1.
DR SUPFAM; SSF90229; SSF90229; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Metal-binding; Reference proteome; RNA-binding; Zinc;
KW Zinc-finger.
FT CHAIN 1..483
FT /note="Zinc finger CCCH domain-containing protein 25"
FT /id="PRO_0000371984"
FT DOMAIN 228..301
FT /note="RRM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT ZN_FING 157..184
FT /note="C3H1-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 298..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..483
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..357
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..395
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..412
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 440..455
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..483
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 483 AA; 54252 MW; 14B511C89457F818 CRC64;
MAHRILRDHE ADGWERSDFP IICESCLGDN PYVRMTKANY DKECKICTRP FTVFRWRPGR
DARYKKTEVC QTCCKLKNVC QVCLLDLEYG LPVQVRDTAL NISTHDSIPK SDVNREFFAE
EHDRKTRAGL DYESSFGKIR PNDTIRMLQR TTPYYKRNRA HICSFFIRGE CTRGDECPYR
HEMPETGELS QQNIKDRYYG VNDPVALKLL GKAGEMGTLE SPEDQSIRTL YVGGLNSRVL
EQDIRDQFYA HGEIESIRIL AEKACAFVTY TTREGAEKAA EELSNRLVVN GQRLKLTWGR
PQVPKPDQDG SNQQGSVAHS GLLPRAVISQ QQNQPPPMLQ YYMHPPPPQP PHQDRPFYPS
MDPQRMGAVS SSKESGSSTS DNRGASSSSY TMPPHGHYPQ HQPYPPPSYG GYMQPPYQQY
PPYHHGHSQQ ADHDYPQQPG PGSRPNPPHP SSVSAPPPDS VSAAPSGSSQ QSADAAVTTG
SSQ
