C3H26_ARATH
ID C3H26_ARATH Reviewed; 453 AA.
AC O48772;
DT 26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Zinc finger CCCH domain-containing protein 26;
DE Short=AtC3H26;
DE AltName: Full=Zinc finger CCCH domain-containing protein ZFN2;
GN Name=ZFN2; OrderedLocusNames=At2g32930; ORFNames=T21L14.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RA Choi S., Lee J., Yi H., Shin B., Choi G.;
RT "Characterization of zinc finger protein ZFN-2 in Arabidopsis thaliana.";
RL Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NOMENCLATURE.
RX PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL BMC Genomics 9:44-44(2008).
RN [5]
RP ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, CLEAVAGE OF INITIATOR
RP METHIONINE [LARGE SCALE ANALYSIS], AND IDENTIFICATION BY MASS SPECTROMETRY
RP [LARGE SCALE ANALYSIS].
RX PubMed=22223895; DOI=10.1074/mcp.m111.015131;
RA Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA Giglione C.;
RT "Comparative large-scale characterisation of plant vs. mammal proteins
RT reveals similar and idiosyncratic N-alpha acetylation features.";
RL Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=O48772-1; Sequence=Displayed;
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DR EMBL; AF138744; AAD33770.1; -; mRNA.
DR EMBL; AC003033; AAB91975.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08763.1; -; Genomic_DNA.
DR PIR; T01114; T01114.
DR RefSeq; NP_565758.1; NM_128853.2. [O48772-1]
DR AlphaFoldDB; O48772; -.
DR BioGRID; 3202; 2.
DR STRING; 3702.AT2G32930.2; -.
DR iPTMnet; O48772; -.
DR PaxDb; O48772; -.
DR PRIDE; O48772; -.
DR ProteomicsDB; 240573; -. [O48772-1]
DR EnsemblPlants; AT2G32930.1; AT2G32930.1; AT2G32930. [O48772-1]
DR GeneID; 817855; -.
DR Gramene; AT2G32930.1; AT2G32930.1; AT2G32930. [O48772-1]
DR KEGG; ath:AT2G32930; -.
DR Araport; AT2G32930; -.
DR eggNOG; KOG1677; Eukaryota.
DR HOGENOM; CLU_033292_2_0_1; -.
DR InParanoid; O48772; -.
DR PhylomeDB; O48772; -.
DR PRO; PR:O48772; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O48772; baseline and differential.
DR Genevisible; O48772; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR Pfam; PF00642; zf-CCCH; 5.
DR SMART; SM00356; ZnF_C3H1; 5.
DR SUPFAM; SSF90229; SSF90229; 4.
DR PROSITE; PS50103; ZF_C3H1; 5.
PE 1: Evidence at protein level;
KW Acetylation; Alternative splicing; DNA-binding; Metal-binding; Nucleus;
KW Reference proteome; Repeat; Zinc; Zinc-finger.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0007744|PubMed:22223895"
FT CHAIN 2..453
FT /note="Zinc finger CCCH domain-containing protein 26"
FT /id="PRO_0000213913"
FT ZN_FING 44..72
FT /note="C3H1-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 95..112
FT /note="C3H1-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 129..157
FT /note="C3H1-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 261..289
FT /note="C3H1-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 307..335
FT /note="C3H1-type 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 360..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 360..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..410
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..453
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 2
FT /note="N-acetylserine"
FT /evidence="ECO:0007744|PubMed:22223895"
SQ SEQUENCE 453 AA; 49747 MW; B5FC49D5FDE5EBA6 CRC64;
MSETQQQVQN STGSIRSPDK IEDTFRRMKV NEDNMEQSSP YPDRPGERDC QFFLRTGQCG
YGNSCRYNHP LTNLPQGIIY YRDQLPERVG QPDCETGACK YGPTCKYHHP KDRNGAGPVL
FNVLGLPMRQ GEKPCPYYMQ TGLCRFGVAC KFHHPHPHSQ PSNGHSAYAM SSFPSVGFPY
ASGMTMVSLP PATYGAIPRP QVPQSQAYMP YMVAPSQGLL PPQGWATYMT ASNPIYNMKT
QLDSSSSASV AVTVTSHHHS FSERAECRFF MNTGTCKYGD DCKYSHPKER LLQSPPTLLN
PIVLPARPGQ PACGNFKAYG FCKFGANCKF DHSMLLNPYN NTGLAMSSLP TPYPYAPPVS
TNLRISSPPS PSDMTTLSNG KPAAAEAQSL ETEKQDDSPT EPEKSEVEDS LPPNGSDSTS
LPNDKPDAET EKQDDDSAEL DSSKVQDSSD KST
