C3H33_ARATH
ID C3H33_ARATH Reviewed; 397 AA.
AC Q8GXX7; Q1EBW8; Q9M8S4; Q9XFB8;
DT 26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Zinc finger CCCH domain-containing protein 33;
DE Short=AtC3H33;
DE AltName: Full=Zinc finger CCCH domain-containing protein ZFN1;
GN Name=ZFN1; OrderedLocusNames=At3g02830; ORFNames=F13E7.23;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RA Choi S., Lee J., Yi H., Shin B., Choi G.;
RT "Characterization of four zinger finger proteins in Arabidopsis.";
RL Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Kim C.J., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NOMENCLATURE.
RX PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL BMC Genomics 9:44-44(2008).
RN [7]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD33769.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=AAF26977.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AF138743; AAD33769.1; ALT_FRAME; mRNA.
DR EMBL; AC018363; AAF26977.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE73864.1; -; Genomic_DNA.
DR EMBL; AK117978; BAC42614.1; -; mRNA.
DR EMBL; BT025966; ABG25055.1; -; mRNA.
DR PIR; T48874; T48874.
DR RefSeq; NP_001325699.1; NM_001337436.1.
DR RefSeq; NP_566183.1; NM_111151.5.
DR AlphaFoldDB; Q8GXX7; -.
DR BioGRID; 6563; 3.
DR DIP; DIP-60324N; -.
DR IntAct; Q8GXX7; 3.
DR STRING; 3702.AT3G02830.1; -.
DR iPTMnet; Q8GXX7; -.
DR PaxDb; Q8GXX7; -.
DR PRIDE; Q8GXX7; -.
DR ProteomicsDB; 239081; -.
DR EnsemblPlants; AT3G02830.1; AT3G02830.1; AT3G02830.
DR GeneID; 821230; -.
DR Gramene; AT3G02830.1; AT3G02830.1; AT3G02830.
DR KEGG; ath:AT3G02830; -.
DR Araport; AT3G02830; -.
DR TAIR; locus:2075477; AT3G02830.
DR eggNOG; KOG1677; Eukaryota.
DR HOGENOM; CLU_033292_2_1_1; -.
DR InParanoid; Q8GXX7; -.
DR OrthoDB; 657700at2759; -.
DR PhylomeDB; Q8GXX7; -.
DR PRO; PR:Q8GXX7; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q8GXX7; baseline and differential.
DR Genevisible; Q8GXX7; AT.
DR GO; GO:0005829; C:cytosol; IDA:TAIR.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; TAS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0048027; F:mRNA 5'-UTR binding; IPI:TAIR.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0004518; F:nuclease activity; TAS:TAIR.
DR GO; GO:0010313; F:phytochrome binding; IPI:TAIR.
DR GO; GO:0017148; P:negative regulation of translation; IMP:TAIR.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR Pfam; PF00642; zf-CCCH; 5.
DR SMART; SM00356; ZnF_C3H1; 5.
DR SUPFAM; SSF90229; SSF90229; 5.
DR PROSITE; PS50103; ZF_C3H1; 5.
PE 1: Evidence at protein level;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Zinc;
KW Zinc-finger.
FT CHAIN 1..397
FT /note="Zinc finger CCCH domain-containing protein 33"
FT /id="PRO_0000213912"
FT ZN_FING 40..68
FT /note="C3H1-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 85..113
FT /note="C3H1-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 131..159
FT /note="C3H1-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 274..302
FT /note="C3H1-type 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 320..348
FT /note="C3H1-type 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 361..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 63
FT /note="F -> V (in Ref. 1; AAD33769)"
FT /evidence="ECO:0000305"
FT CONFLICT 88
FT /note="Q -> H (in Ref. 1; AAD33769)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 397 AA; 44181 MW; 2A4A78A1BEC0A1B3 CRC64;
MDFNAGVPMS SLSPLMNQDA MWQMNLSSDE TMETGSYPER PGEPDCSYYI RTGLCRFGST
CRFNHPRDRE LVIATARMRG EYPERIGQPE CEYYLKTGTC KFGVTCKFHH PRNKAGIAGR
VSLNMLGYPL RSNEVDCAYF LRTGHCKFGG TCKFNHPQPQ PTNMMVPTSG QQSYPWSRAS
FIASPRWQDP SSYASLIMPQ GVVPVQGWNP YSGQLGSVSP SGTGNDQNYR NLQQNETIES
GSQSQGSFSG YNPGSSVPLG GYYALPRENV FPERPGQPEC QFYMKTGDCK FGTVCKFHHP
RDRQAPPPDC LLSSIGLPLR PGEPLCVFYT RYGICKFGPS CKFDHPMRVF TYDNTASETD
EVVETSTGKS RRLSVSETRQ AATTSSGKDT TIDNTQQ
