C3H40_ARATH
ID C3H40_ARATH Reviewed; 437 AA.
AC Q93XW7; Q9LSY3;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 25-MAY-2022, entry version 106.
DE RecName: Full=Zinc finger CCCH domain-containing protein 40;
DE Short=AtC3H40;
GN OrderedLocusNames=At3g21810; ORFNames=MSD21.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NOMENCLATURE.
RX PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL BMC Genomics 9:44-44(2008).
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-259, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=cv. Columbia;
RX PubMed=19245862; DOI=10.1016/j.jprot.2009.02.004;
RA Jones A.M.E., MacLean D., Studholme D.J., Serna-Sanz A., Andreasson E.,
RA Rathjen J.P., Peck S.C.;
RT "Phosphoproteomic analysis of nuclei-enriched fractions from Arabidopsis
RT thaliana.";
RL J. Proteomics 72:439-451(2009).
RN [6]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-259, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- INTERACTION:
CC Q93XW7; Q9SFV2: FHA2; NbExp=3; IntAct=EBI-15195363, EBI-15191747;
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB02843.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB025634; BAB02843.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE76554.1; -; Genomic_DNA.
DR EMBL; AY059899; AAL24381.1; -; mRNA.
DR EMBL; AY128791; AAM91191.1; -; mRNA.
DR RefSeq; NP_566691.1; NM_113076.3.
DR AlphaFoldDB; Q93XW7; -.
DR SMR; Q93XW7; -.
DR BioGRID; 7067; 9.
DR IntAct; Q93XW7; 9.
DR STRING; 3702.AT3G21810.1; -.
DR iPTMnet; Q93XW7; -.
DR PaxDb; Q93XW7; -.
DR PRIDE; Q93XW7; -.
DR ProteomicsDB; 240576; -.
DR EnsemblPlants; AT3G21810.1; AT3G21810.1; AT3G21810.
DR GeneID; 821735; -.
DR Gramene; AT3G21810.1; AT3G21810.1; AT3G21810.
DR KEGG; ath:AT3G21810; -.
DR Araport; AT3G21810; -.
DR TAIR; locus:2093044; AT3G21810.
DR eggNOG; ENOG502QQDM; Eukaryota.
DR HOGENOM; CLU_052898_0_1_1; -.
DR InParanoid; Q93XW7; -.
DR OMA; MAGNHFS; -.
DR OrthoDB; 765278at2759; -.
DR PhylomeDB; Q93XW7; -.
DR PRO; PR:Q93XW7; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q93XW7; baseline and differential.
DR Genevisible; Q93XW7; AT.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR045868; Znf_C3H13/40.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR PANTHER; PTHR38160; PTHR38160; 1.
DR Pfam; PF00642; zf-CCCH; 1.
DR SUPFAM; SSF90229; SSF90229; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 1: Evidence at protein level;
KW Coiled coil; DNA-binding; Metal-binding; Phosphoprotein;
KW Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..437
FT /note="Zinc finger CCCH domain-containing protein 40"
FT /id="PRO_0000371995"
FT ZN_FING 6..33
FT /note="C3H1-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 35..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 266..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 380..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 145..244
FT /evidence="ECO:0000255"
FT COMPBIAS 40..90
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..289
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..319
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 345..360
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..437
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 259
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19245862,
FT ECO:0007744|PubMed:19376835"
SQ SEQUENCE 437 AA; 50519 MW; D8F284DFC75CE067 CRC64;
MSGSSMYKTK LCILFNKTGD CSRPNCTFAH GNAELRRPGE SSFTGRRHNM DSDLRDRRHN
MDSDLRDRLG RQFSPERRPS LDRSGRRVQR FSGHDNSMPF ENRRDKDYRE NRRFDERRDY
AGGLKVGNRI EDRAEDGRNK FHGYNNVLEE QLKDVEMDVK MLTDDKLRLE ASVERKAHEV
DILTSRIQEL ETQLDREKDE CRRITSSSKK FVKEYNRFLR AQDDLKRSEA RLQKLGNQLS
TYLAGSEGNN RDVGLDIVSD EETNGRNLRT ACDPHNELQN TSSLSRKKHY VDQYTTKEPV
EDGLIGRGEE EKVENEKKRP PCWNMLSSKS YSEEESGAWN DEDTINRSSS KEDNWKRRRF
SIGTSATDKV ILSTSMAARE FDDVAESEEE NPEAANGSPL ISLPPPPPFR DAHVQRDEDD
VNGDVMEQKK AYDDDSV
