C3H44_ARATH
ID C3H44_ARATH Reviewed; 1292 AA.
AC Q9SD34;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 31-MAY-2011, sequence version 3.
DT 25-MAY-2022, entry version 131.
DE RecName: Full=Zinc finger CCCH domain-containing protein 44;
DE Short=AtC3H44;
GN OrderedLocusNames=At3g51120; ORFNames=F24M12.160;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NOMENCLATURE.
RX PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL BMC Genomics 9:44-44(2008).
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB62634.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL132980; CAB62634.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; T45743; T45743.
DR AlphaFoldDB; Q9SD34; -.
DR SMR; Q9SD34; -.
DR STRING; 3702.AT3G51120.1; -.
DR PaxDb; Q9SD34; -.
DR PRIDE; Q9SD34; -.
DR ProteomicsDB; 240496; -.
DR Araport; AT3G51120; -.
DR TAIR; locus:2080863; AT3G51120.
DR eggNOG; KOG1081; Eukaryota.
DR eggNOG; KOG1862; Eukaryota.
DR eggNOG; KOG1946; Eukaryota.
DR HOGENOM; CLU_002000_1_0_1; -.
DR InParanoid; Q9SD34; -.
DR PRO; PR:Q9SD34; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9SD34; baseline and differential.
DR Genevisible; Q9SD34; AT.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00072; GYF; 1.
DR Gene3D; 1.10.245.10; -; 1.
DR Gene3D; 3.30.1490.40; -; 1.
DR Gene3D; 3.30.40.10; -; 1.
DR Gene3D; 3.90.70.200; -; 1.
DR InterPro; IPR003169; GYF.
DR InterPro; IPR035445; GYF-like_dom_sf.
DR InterPro; IPR004343; Plus-3_dom.
DR InterPro; IPR036128; Plus3-like_sf.
DR InterPro; IPR019835; SWIB_domain.
DR InterPro; IPR036885; SWIB_MDM2_dom_sf.
DR InterPro; IPR003121; SWIB_MDM2_domain.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF02213; GYF; 1.
DR Pfam; PF03126; Plus-3; 1.
DR Pfam; PF02201; SWIB; 1.
DR Pfam; PF00642; zf-CCCH; 1.
DR SMART; SM00444; GYF; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00719; Plus3; 1.
DR SMART; SM00151; SWIB; 1.
DR SUPFAM; SSF159042; SSF159042; 1.
DR SUPFAM; SSF47592; SSF47592; 1.
DR SUPFAM; SSF55277; SSF55277; 1.
DR SUPFAM; SSF57903; SSF57903; 1.
DR SUPFAM; SSF90229; SSF90229; 1.
DR PROSITE; PS50829; GYF; 1.
DR PROSITE; PS51360; PLUS3; 1.
DR PROSITE; PS51925; SWIB_MDM2; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding; Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..1292
FT /note="Zinc finger CCCH domain-containing protein 44"
FT /id="PRO_0000371998"
FT DOMAIN 313..396
FT /note="SWIB/MDM2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01273"
FT DOMAIN 453..586
FT /note="Plus3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00693"
FT DOMAIN 716..770
FT /note="GYF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00101"
FT ZN_FING 110..176
FT /note="PHD-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00146"
FT ZN_FING 1267..1292
FT /note="C3H1-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 72..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 256..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 401..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 624..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 777..832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 876..915
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1170..1245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..281
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..417
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 655..675
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..722
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 802..831
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 880..915
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1188..1218
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1226..1245
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1292 AA; 142092 MW; 4CCA51445844BDBE CRC64;
MENQQKQLQQ GVPELASLAG REESSVRGID LMRVDQCEEI GVNQVPALSV PASTVAGAVA
VPMSNEQEVK VIDEAAPIKR KRGRPPRAQA NTPLHIRPPP PPPKKEDKEE DVCFICFDGG
DLVLCDRRNC PKAYHPACIK RDEAFFRTTA KWNCGWHICG TCQKASSYMC YTCTFSVCKR
CIKDADYVIV RGNMGLCGTC IKPIMLIENI AQGDNEAVKV DFDDKLSWEY LFKVYWLCLK
EELSLTVDEL TRANNPWKEV PNTAPKVESQ NDHTNNRALD VAVNGTKRRR TSDSPTLPNK
LDGKNPSNIL KKAPGDTSWA TKELLEFVSF MKNGDTSVLS QFDVQGLLLD YIKKKNLRDP
LQKSQVLCDQ MLVKLFGKQR VGHFEMLKLL ESHVLIQEKP KGAKTTNGET THAVPSQIEE
DSVHDPMVRD RRRKMRRKTD GRVQNENLDA YAAIDVHNIN LIYLRRKFLE SLLDDINKVD
EKVVGTILRI KVSGSDQKLD IHRLVQVVGT SKAIASYQLG AKTTDVMLEI LNLDKREVIS
IDQLSDQNIT EDECKRLRQS IKCGLNKRLT VVDILKTAAT LQAMRINEAL EAEILKLNHL
RDRAKKLELL KSPEERQRLL QEVPEVHTDP SMDPSHALSE DAGLGTRKQD NHVKAQSKGP
QNKGVNLNNV GNNVQKKYDA PILRSRNNVH ADKDDCSKVH NNSSNIQETG KDDEESEIWH
YRDPTGKTQG PFSMVQLRRW KSSGHFPPYL RIWRAHENQD ESVLLTDALA GRFDKATTLP
SSSSLPQELK PSPHDSGRTG ADVNCLQKNQ MPVNTSATSS SSSTVTAHSN DPKEKQVVAL
VACSGKVEDG NSVRPQPQVS CPASISVVPG HVVTPDVRET PGTDQYNTVR ADGNHNTTKT
LEDETNGGSV SINGSVHAPN LNQESHFLDF PSPTPKSSPE DLEAQAAETI QSLSSCVLVK
GPSGVTWSTT TTSTTDAATT TSSVVVTGGQ LPQVIQQNTV VLAAPSVKPI ELAADHATAT
QTSDNTQVAQ ASGWPAIVAD PDECDESVSD LLAEVEAMEQ NGLPSSPTST FHCDDDDDLK
GPEKDFFNPV ARMSLTPETC RLDVSQTSIL DNVSAGKSSM LTEAKDNTPF SHCGTAGPEL
LLFAPPPPPP TAISHDLTLT TTALRLGSET TVEAGTVERL PKSVLGVSSE PSPRSLSSHD
SSSARGSTER SPRVSQPKRS SGHSRDRQWL NNGHNSSFNN SHNNRQWPYS NSHGYDHGSG
SYAAHPPKGL KICKFYESGY CKRGASCSFW HP
