C3H52_ARATH
ID C3H52_ARATH Reviewed; 240 AA.
AC Q9FG30; Q8LC70;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 129.
DE RecName: Full=Zinc finger CCCH domain-containing protein 52;
DE Short=AtC3H52;
GN OrderedLocusNames=At5g06770; ORFNames=MPH15.13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NOMENCLATURE.
RX PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL BMC Genomics 9:44-44(2008).
CC -!- INTERACTION:
CC Q9FG30; Q9SHZ6: UBA1A; NbExp=3; IntAct=EBI-4440997, EBI-346271;
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DR EMBL; AP002032; BAB09811.1; -; Genomic_DNA.
DR EMBL; CP002688; AED91063.1; -; Genomic_DNA.
DR EMBL; AK117974; BAC42611.1; -; mRNA.
DR EMBL; BT005260; AAO63324.1; -; mRNA.
DR EMBL; AY086759; AAM63810.1; -; mRNA.
DR RefSeq; NP_196295.1; NM_120760.3.
DR AlphaFoldDB; Q9FG30; -.
DR SMR; Q9FG30; -.
DR BioGRID; 15845; 11.
DR IntAct; Q9FG30; 11.
DR STRING; 3702.AT5G06770.1; -.
DR PaxDb; Q9FG30; -.
DR PRIDE; Q9FG30; -.
DR ProteomicsDB; 239158; -.
DR EnsemblPlants; AT5G06770.1; AT5G06770.1; AT5G06770.
DR GeneID; 830566; -.
DR Gramene; AT5G06770.1; AT5G06770.1; AT5G06770.
DR KEGG; ath:AT5G06770; -.
DR Araport; AT5G06770; -.
DR TAIR; locus:2170169; AT5G06770.
DR eggNOG; KOG1677; Eukaryota.
DR HOGENOM; CLU_045191_2_0_1; -.
DR InParanoid; Q9FG30; -.
DR OrthoDB; 1183911at2759; -.
DR PhylomeDB; Q9FG30; -.
DR PRO; PR:Q9FG30; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FG30; baseline and differential.
DR Genevisible; Q9FG30; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IDA:TAIR.
DR GO; GO:1900057; P:positive regulation of leaf senescence; IMP:TAIR.
DR GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR GO; GO:2000028; P:regulation of photoperiodism, flowering; IGI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR Gene3D; 3.30.1370.10; -; 1.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF00642; zf-CCCH; 2.
DR SMART; SM00322; KH; 1.
DR SMART; SM00356; ZnF_C3H1; 2.
DR SUPFAM; SSF54791; SSF54791; 1.
DR SUPFAM; SSF90229; SSF90229; 2.
DR PROSITE; PS50084; KH_TYPE_1; 1.
DR PROSITE; PS50103; ZF_C3H1; 2.
PE 1: Evidence at protein level;
KW DNA-binding; Metal-binding; Reference proteome; Repeat; RNA-binding; Zinc;
KW Zinc-finger.
FT CHAIN 1..240
FT /note="Zinc finger CCCH domain-containing protein 52"
FT /id="PRO_0000372005"
FT DOMAIN 113..177
FT /note="KH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00117"
FT ZN_FING 36..64
FT /note="C3H1-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 205..232
FT /note="C3H1-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 81..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 74
FT /note="T -> K (in Ref. 5; AAM63810)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 240 AA; 25368 MW; 4C6C3FF8900A62A4 CRC64;
MDARKRGRPE AAASHNSNGG FKRSKQEMES ISTGLGSKSK PCTKFFSTSG CPFGDNCHFL
HYVPGGYNAA AQMTNLRPPV SQVSRNMQGS GGPGGRFSGR GDPGSGPVSI FGASTSKISV
DASLAGAIIG KGGIHSKQIC RETGAKLSIK DHERDPNLKI IELEGTFEQI NVASGMVREL
IGRLGSVKKP QGIGGPEGKP HPGSNYKTKI CDRYSKGNCT YGDRCHFAHG ESELRRSGIA
