ID   C3H53_ARATH             Reviewed;         363 AA.
AC   Q9FL40; A0MFE0;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 146.
DE   RecName: Full=Zinc finger CCCH domain-containing protein 53;
DE            Short=AtC3H53;
GN   OrderedLocusNames=At5g07060; ORFNames=MOJ9.23;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9679202; DOI=10.1093/dnares/5.2.131;
RA   Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence
RT   features of the regions of 1,381,565 bp covered by twenty one physically
RT   assigned P1 and TAC clones.";
RL   DNA Res. 5:131-145(1998).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
RN   [4]
RP   NOMENCLATURE.
RX   PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA   Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT   "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL   BMC Genomics 9:44-44(2008).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=1;
CC         Comment=A number of isoforms are produced. According to EST
CC         sequences.;
CC       Name=1;
CC         IsoId=Q9FL40-1; Sequence=Displayed;
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABK28682.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AB010697; BAB11164.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED91103.1; -; Genomic_DNA.
DR   EMBL; DQ446923; ABE66134.1; -; mRNA.
DR   EMBL; DQ653266; ABK28682.1; ALT_SEQ; mRNA.
DR   RefSeq; NP_196323.1; NM_120788.2. [Q9FL40-1]
DR   AlphaFoldDB; Q9FL40; -.
DR   SMR; Q9FL40; -.
DR   BioGRID; 15876; 1.
DR   STRING; 3702.AT5G07060.1; -.
DR   PaxDb; Q9FL40; -.
DR   EnsemblPlants; AT5G07060.1; AT5G07060.1; AT5G07060. [Q9FL40-1]
DR   GeneID; 830597; -.
DR   Gramene; AT5G07060.1; AT5G07060.1; AT5G07060. [Q9FL40-1]
DR   KEGG; ath:AT5G07060; -.
DR   Araport; AT5G07060; -.
DR   TAIR; locus:2169429; AT5G07060.
DR   eggNOG; KOG0153; Eukaryota.
DR   HOGENOM; CLU_027112_2_0_1; -.
DR   InParanoid; Q9FL40; -.
DR   OrthoDB; 1272857at2759; -.
DR   PhylomeDB; Q9FL40; -.
DR   PRO; PR:Q9FL40; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FL40; baseline and differential.
DR   Genevisible; Q9FL40; AT.
DR   GO; GO:0000974; C:Prp19 complex; IBA:GO_Central.
DR   GO; GO:0071006; C:U2-type catalytic step 1 spliceosome; IBA:GO_Central.
DR   GO; GO:0071007; C:U2-type catalytic step 2 spliceosome; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0036002; F:pre-mRNA binding; IBA:GO_Central.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR   GO; GO:0017070; F:U6 snRNA binding; IBA:GO_Central.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR039171; Cwc2/Slt11.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000571; Znf_CCCH.
DR   InterPro; IPR036855; Znf_CCCH_sf.
DR   PANTHER; PTHR14089; PTHR14089; 1.
DR   SMART; SM00356; ZnF_C3H1; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   SUPFAM; SSF90229; SSF90229; 1.
DR   PROSITE; PS50103; ZF_C3H1; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; DNA-binding; Metal-binding; Reference proteome;
KW   RNA-binding; Zinc; Zinc-finger.
FT   CHAIN           1..363
FT                   /note="Zinc finger CCCH domain-containing protein 53"
FT                   /id="PRO_0000372006"
FT   DOMAIN          225..310
FT                   /note="RRM"
FT   ZN_FING         154..181
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   REGION          281..348
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        281..300
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        307..341
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   363 AA;  41755 MW;  F645F793D67C56F3 CRC64;
     MSHRDHGADG WESADFPITC ESCFGDNPYM RMTRADYDKE CKICSRPFTA FRWRPGRNAR
     FKKTEICQTC SKLKNVCQVC LLDLGFGLPV QVRDSALNIN SHYSVPMSHV NREYFADEHD
     PKTRAGLDYE SSFGKMQPND TILKLQRRTP SYEKNRPKIC SFYTIGQCKR GAECSFRHEM
     PETGELSHQN IRDRYYSVND PVAMKLLRKA GEMGTLEPPE DESIKTLYVG GLNSRIFEQD
     IHDHFYAYGE MESIRVMAED GKYDQSGSNQ QQQGSIAHTG LISQQQNQHS QMQQYYMQPP
     PPNEYSHYPS MDTQRMGAAF STQESDGSST SENNRAYSSY SYPMPPHQPY PTPPPYIDIY
     IYI