C3H54_ARATH
ID C3H54_ARATH Reviewed; 245 AA.
AC O65036; A0MFE4;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Zinc finger CCCH domain-containing protein 54;
DE Short=AtC3H54;
DE AltName: Full=Tandem CCCH Zinc Finger protein 6 {ECO:0000303|PubMed:26978070};
DE Short=AtTZF6 {ECO:0000303|PubMed:26978070};
GN Name=TZF6 {ECO:0000303|PubMed:26978070};
GN Synonyms=PEI1 {ECO:0000312|EMBL:AAC05744.1};
GN OrderedLocusNames=At5g07500 {ECO:0000312|Araport:AT5G07500};
GN ORFNames=T2I1.210 {ECO:0000312|EMBL:CAB87939.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, AND TISSUE
RP SPECIFICITY.
RX PubMed=9501112; DOI=10.2307/3870596;
RA Li Z., Thomas T.L.;
RT "PEI1, an embryo-specific zinc finger protein gene required for heart-stage
RT embryo formation in Arabidopsis.";
RL Plant Cell 10:383-398(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [5]
RP NOMENCLATURE.
RX PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL BMC Genomics 9:44-44(2008).
RN [6]
RP INTERACTION WITH MARD1 AND RD21A.
RX PubMed=26978070; DOI=10.1371/journal.pone.0151574;
RA Bogamuwa S., Jang J.C.;
RT "Plant tandem CCCH zinc finger proteins interact with ABA, drought, and
RT stress response regulators in processing-bodies and stress granules.";
RL PLoS ONE 11:E0151574-E0151574(2016).
CC -!- FUNCTION: Embryo-specific transcription factor required at the globular
CC to heart stage transition in embryo development.
CC {ECO:0000269|PubMed:9501112}.
CC -!- SUBUNIT: Interacts with MARD1/FLZ9 and RD21A.
CC {ECO:0000269|PubMed:26978070}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305|PubMed:9501112}.
CC -!- TISSUE SPECIFICITY: Specifically expressed in embryo (at protein
CC level). {ECO:0000269|PubMed:9501112}.
CC -!- MISCELLANEOUS: Plants lacking PEI1 produce white seeds in which embryo
CC development does not progress through heart stage.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABK28686.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AF050463; AAC05744.1; -; mRNA.
DR EMBL; AL163912; CAB87939.1; -; Genomic_DNA.
DR EMBL; CP002688; AED91166.1; -; Genomic_DNA.
DR EMBL; DQ446927; ABE66138.1; -; mRNA.
DR EMBL; DQ653270; ABK28686.1; ALT_SEQ; mRNA.
DR PIR; T49889; T49889.
DR RefSeq; NP_196367.1; NM_120832.2.
DR AlphaFoldDB; O65036; -.
DR BioGRID; 15921; 1.
DR STRING; 3702.AT5G07500.1; -.
DR PaxDb; O65036; -.
DR PRIDE; O65036; -.
DR ProteomicsDB; 240519; -.
DR EnsemblPlants; AT5G07500.1; AT5G07500.1; AT5G07500.
DR GeneID; 830642; -.
DR Gramene; AT5G07500.1; AT5G07500.1; AT5G07500.
DR KEGG; ath:AT5G07500; -.
DR Araport; AT5G07500; -.
DR TAIR; locus:2183339; AT5G07500.
DR eggNOG; KOG1595; Eukaryota.
DR HOGENOM; CLU_044407_1_1_1; -.
DR InParanoid; O65036; -.
DR OMA; RRYTYCA; -.
DR OrthoDB; 905042at2759; -.
DR PhylomeDB; O65036; -.
DR PRO; PR:O65036; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; O65036; baseline and differential.
DR Genevisible; O65036; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR InterPro; IPR045234; Unkempt-like.
DR InterPro; IPR000571; Znf_CCCH.
DR PANTHER; PTHR14493; PTHR14493; 1.
DR Pfam; PF00642; zf-CCCH; 1.
DR SMART; SM00356; ZnF_C3H1; 2.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 1: Evidence at protein level;
KW Differentiation; DNA-binding; Metal-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..245
FT /note="Zinc finger CCCH domain-containing protein 54"
FT /id="PRO_0000372007"
FT ZN_FING 92..119
FT /note="C3H1-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 175..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..204
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 245 AA; 28175 MW; 6C67D3BD022A9384 CRC64;
MLKSASPMAF YDIGEQQYST FGYILSKPGN AGAYEIDPSI PNIDDAIYGS DEFRMYAYKI
KRCPRTRSHD WTECPYAHRG EKATRRDPRR YTYCAVACPA FRNGACHRGD SCEFAHGVFE
YWLHPARYRT RACNAGNLCQ RKVCFFAHAP EQLRQSEGKH RCRYAYRPVR ARGGGNGDGV
TMRMDDEGYD TSRSPVRSGK DDLDSNEEKV LLKCWSRMSI VDDHYEPSDL DLDLSHFDWI
SELVD
