C3H56_ARATH
ID C3H56_ARATH Reviewed; 706 AA.
AC Q9LXV4; Q8L3W6;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 136.
DE RecName: Full=Zinc finger CCCH domain-containing protein 56;
DE Short=AtC3H56;
GN OrderedLocusNames=At5g12850; ORFNames=T24H18.20;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NOMENCLATURE.
RX PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL BMC Genomics 9:44-44(2008).
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DR EMBL; AL353013; CAB88249.1; -; Genomic_DNA.
DR EMBL; CP002688; AED91821.1; -; Genomic_DNA.
DR EMBL; AY099761; AAM20612.1; -; mRNA.
DR EMBL; AY128891; AAM91291.1; -; mRNA.
DR EMBL; AK227145; BAE99190.1; -; mRNA.
DR PIR; T49899; T49899.
DR RefSeq; NP_196789.1; NM_121288.5.
DR AlphaFoldDB; Q9LXV4; -.
DR SMR; Q9LXV4; -.
DR STRING; 3702.AT5G12850.1; -.
DR iPTMnet; Q9LXV4; -.
DR PaxDb; Q9LXV4; -.
DR PRIDE; Q9LXV4; -.
DR ProteomicsDB; 239113; -.
DR EnsemblPlants; AT5G12850.1; AT5G12850.1; AT5G12850.
DR GeneID; 831125; -.
DR Gramene; AT5G12850.1; AT5G12850.1; AT5G12850.
DR KEGG; ath:AT5G12850; -.
DR Araport; AT5G12850; -.
DR TAIR; locus:2182250; AT5G12850.
DR eggNOG; KOG1595; Eukaryota.
DR HOGENOM; CLU_015068_1_0_1; -.
DR InParanoid; Q9LXV4; -.
DR OMA; ELNLSCG; -.
DR OrthoDB; 905042at2759; -.
DR PhylomeDB; Q9LXV4; -.
DR PRO; PR:Q9LXV4; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LXV4; baseline and differential.
DR Genevisible; Q9LXV4; AT.
DR GO; GO:0005737; C:cytoplasm; HDA:TAIR.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR Gene3D; 1.25.40.20; -; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR045234; Unkempt-like.
DR InterPro; IPR000571; Znf_CCCH.
DR PANTHER; PTHR14493; PTHR14493; 1.
DR Pfam; PF12796; Ank_2; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00356; ZnF_C3H1; 1.
DR SUPFAM; SSF48403; SSF48403; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS50103; ZF_C3H1; 2.
PE 2: Evidence at transcript level;
KW ANK repeat; DNA-binding; Metal-binding; Phosphoprotein; Reference proteome;
KW Repeat; Zinc; Zinc-finger.
FT CHAIN 1..706
FT /note="Zinc finger CCCH domain-containing protein 56"
FT /id="PRO_0000372009"
FT REPEAT 83..113
FT /note="ANK 1"
FT REPEAT 118..150
FT /note="ANK 2"
FT ZN_FING 302..324
FT /note="C3H1-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT ZN_FING 332..356
FT /note="C3H1-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT REGION 211..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 396..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 545..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 652..692
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..564
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 573..589
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..616
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 652..688
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 568
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P93755"
FT CONFLICT 32
FT /note="A -> V (in Ref. 3; AAM91291/AAM20612)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 706 AA; 77775 MW; F07AE3E0FC9BE974 CRC64;
MCGLAKKLDI EDTLTSLSDQ ENESLAKPMN DAAEWEHSFS ALLEFAADND VEGFRRQLSD
VSCINQMGLW YRRQRFVRRM VLEQRTPLMV ASLYGSLDVV KFILSFPEAE LNLSCGPDKS
TALHCAASGA SVNSLDVVKL LLSVGADPNI PDAHGNRPVD VLVVSPHAPG LRTILEEILK
KDEIISEDLH ASSSSLGSSF RSLSSSPDNG SSLLSLDSVS SPTKPHGTDV TFASEKKEYP
IDPSLPDIKS GIYSTDEFRM FSFKIRPCSR AYSHDWTECP FAHPGENARR RDPRKFHYTC
VPCPDFKKGS CKQGDMCEYA HGVFECWLHP AQYRTRLCKD GMGCNRRVCF FAHANEELRP
LYPSTGSGLP SPRASSAVSA STMDMASVLN MLPGSPSAAQ HSFTPPISPS GNGSMPHSSM
GWPQQNIPAL NLPGSNIQLS RLRSSLNARD IPSEQLSMLH EFEMQRQLAG DMHSPRFMNH
SARPKTLNPS NLEELFSAEV ASPRFSDQLA VSSVLSPSHK SALLNQLQNN KQSMLSPIKT
NLMSSPKNVE QHSLLQQASS PRGGEPISPM NARMKQQLHS RSLSSRDFGS SLPRDLMPTD
SGSPLSPWSS WDQTHGSKVD WSVQSDELGR LRKSHSLANN PNREADVSWA QQMLKDSSSP
RNGNRVVNMN GARPLTQGGS SVNPHNSDTR ESDILDAWLE QLHLDR
