ID   C3H59_ARATH             Reviewed;         472 AA.
AC   Q9FKR9; Q9FNZ0;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 135.
DE   RecName: Full=Zinc finger CCCH domain-containing protein 59;
DE            Short=AtC3H59;
DE   AltName: Full=Zinc finger CCCH domain and WD40 repeat-containing protein 3;
GN   Name=ZFWD3; OrderedLocusNames=At5g40880; ORFNames=MHK7.11;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9679202; DOI=10.1093/dnares/5.2.131;
RA   Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence
RT   features of the regions of 1,381,565 bp covered by twenty one physically
RT   assigned P1 and TAC clones.";
RL   DNA Res. 5:131-145(1998).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Kim C.J., Bautista V.R., Chen H., De Los Reyes C., Wu S.Y., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 27-472.
RC   STRAIN=cv. Columbia;
RX   PubMed=11137290; DOI=10.1016/s0378-1119(00)00446-7;
RA   Terol J., Bargues M., Perez-Alonso M.;
RT   "ZFWD: a novel subfamily of plant proteins containing a C3H zinc finger and
RT   seven WD40 repeats.";
RL   Gene 260:45-53(2000).
RN   [5]
RP   NOMENCLATURE.
RX   PubMed=18221561; DOI=10.1186/1471-2164-9-44;
RA   Wang D., Guo Y., Wu C., Yang G., Li Y., Zheng C.;
RT   "Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.";
RL   BMC Genomics 9:44-44(2008).
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DR   EMBL; AB011477; BAB11350.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED94611.1; -; Genomic_DNA.
DR   EMBL; BT030400; ABO45703.1; -; mRNA.
DR   EMBL; AJ252065; CAC19849.1; -; mRNA.
DR   RefSeq; NP_198904.1; NM_123453.3.
DR   AlphaFoldDB; Q9FKR9; -.
DR   SMR; Q9FKR9; -.
DR   BioGRID; 19340; 3.
DR   IntAct; Q9FKR9; 3.
DR   STRING; 3702.AT5G40880.1; -.
DR   PaxDb; Q9FKR9; -.
DR   PRIDE; Q9FKR9; -.
DR   EnsemblPlants; AT5G40880.1; AT5G40880.1; AT5G40880.
DR   GeneID; 834089; -.
DR   Gramene; AT5G40880.1; AT5G40880.1; AT5G40880.
DR   KEGG; ath:AT5G40880; -.
DR   Araport; AT5G40880; -.
DR   TAIR; locus:2164456; AT5G40880.
DR   eggNOG; KOG0274; Eukaryota.
DR   HOGENOM; CLU_037680_1_0_1; -.
DR   InParanoid; Q9FKR9; -.
DR   OrthoDB; 757685at2759; -.
DR   PhylomeDB; Q9FKR9; -.
DR   PRO; PR:Q9FKR9; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FKR9; baseline and differential.
DR   Genevisible; Q9FKR9; AT.
DR   GO; GO:0005634; C:nucleus; IDA:TAIR.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR000571; Znf_CCCH.
DR   InterPro; IPR036855; Znf_CCCH_sf.
DR   Pfam; PF00400; WD40; 3.
DR   Pfam; PF00642; zf-CCCH; 1.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 5.
DR   SMART; SM00356; ZnF_C3H1; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   SUPFAM; SSF90229; SSF90229; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
DR   PROSITE; PS50103; ZF_C3H1; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Reference proteome; Repeat; WD repeat; Zinc;
KW   Zinc-finger.
FT   CHAIN           1..472
FT                   /note="Zinc finger CCCH domain-containing protein 59"
FT                   /id="PRO_0000372010"
FT   REPEAT          185..226
FT                   /note="WD 1"
FT   REPEAT          261..301
FT                   /note="WD 2"
FT   REPEAT          310..347
FT                   /note="WD 3"
FT   REPEAT          350..387
FT                   /note="WD 4"
FT   REPEAT          436..472
FT                   /note="WD 5"
FT   ZN_FING         145..172
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   REGION          87..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        94..138
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   472 AA;  51297 MW;  A96BD108956F7213 CRC64;
     MGHQSSWMKQ TVIDSVVQSS KVGVFSMFSM DYKAPRKYSH GRNFGVARQQ DFAADIVTRR
     PYAPYDNGMK KGPNKLSRNL VWTSKEYKSP EGNRPRQNAA NGSAKPQVIG TGHRVSNQPR
     KNAVYGPRSS SLSDTRGCGP RLNGSPKKSV CNFWKDGNCK KGEKCQFLHS WSCFPGLAMV
     AALEGHKNDI KGIALPQGSD KLFSVSGDGT LLIWDCNSGQ CVRSINLQAE AGSLISEGPW
     VFLGLPNAVK AFNVQNSKDV HLEGVVGQVH AMTAANGMLF AGTSSGSILV WKATDSESDP
     FKYLTSLEGH HSGEVTCFVV GGEVLYSGSV DKTIKVWDLN TLQCRMTLKQ HIGTVTSLLC
     WDKCLISSSL DGTIKLWACS ENESLKVVQT RKQELSVHTL CGMHDAEAKP IMFCSYQNGA
     VGIFDLPSFE ERGKMFSTQT ICTLTIGPGG LLFSGDKSGN LRVWSLASGT KV