ID   TSF_ARATH               Reviewed;         175 AA.
AC   Q9S7R5;
DT   05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 132.
DE   RecName: Full=Protein TWIN SISTER of FT;
DE   AltName: Full=TFL1-like protein;
GN   Name=TSF; OrderedLocusNames=At4g20370; ORFNames=F9F13.20;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10583960; DOI=10.1126/science.286.5446.1960;
RA   Kobayashi Y., Kaya H., Goto K., Iwabuchi M., Araki T.;
RT   "A pair of related genes with antagonistic roles in mediating flowering
RT   signals.";
RL   Science 286:1960-1962(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10583961; DOI=10.1126/science.286.5446.1962;
RA   Kardailsky I., Shukla V.K., Ahn J.H., Dagenais N., Christensen S.K.,
RA   Nguyen J.T., Chory J., Harrison M.J., Weigel D.;
RT   "Activation tagging of the floral inducer FT.";
RL   Science 286:1962-1965(1999).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617198; DOI=10.1038/47134;
RA   Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA   Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA   Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA   de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA   Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA   Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA   Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA   Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA   Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA   Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA   Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA   Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA   Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA   Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA   Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA   Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA   Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA   Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA   Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA   Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA   Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA   Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA   Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA   Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA   Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA   Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA   de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA   Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA   Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA   Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA   Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA   Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA   Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA   Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA   Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA   Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA   O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA   Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA   Martienssen R., McCombie W.R.;
RT   "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL   Nature 402:769-777(1999).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- FUNCTION: May form complexes with phosphorylated ligands by interfering
CC       with kinases and their effectors. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the phosphatidylethanolamine-binding protein
CC       family. {ECO:0000305}.
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DR   EMBL; AF152907; AAF03937.1; -; mRNA.
DR   EMBL; AB027506; BAA77840.1; -; mRNA.
DR   EMBL; AL080253; CAB45803.1; -; Genomic_DNA.
DR   EMBL; AL161553; CAB79037.1; -; Genomic_DNA.
DR   EMBL; CP002687; AEE84314.1; -; Genomic_DNA.
DR   PIR; T52446; T52446.
DR   RefSeq; NP_193770.1; NM_118156.2.
DR   AlphaFoldDB; Q9S7R5; -.
DR   SMR; Q9S7R5; -.
DR   BioGRID; 13076; 2.
DR   IntAct; Q9S7R5; 2.
DR   STRING; 3702.AT4G20370.1; -.
DR   PaxDb; Q9S7R5; -.
DR   PRIDE; Q9S7R5; -.
DR   ProteomicsDB; 232351; -.
DR   EnsemblPlants; AT4G20370.1; AT4G20370.1; AT4G20370.
DR   GeneID; 827785; -.
DR   Gramene; AT4G20370.1; AT4G20370.1; AT4G20370.
DR   KEGG; ath:AT4G20370; -.
DR   Araport; AT4G20370; -.
DR   TAIR; locus:2005521; AT4G20370.
DR   eggNOG; KOG3346; Eukaryota.
DR   HOGENOM; CLU_043994_6_1_1; -.
DR   InParanoid; Q9S7R5; -.
DR   OMA; TGCVMSD; -.
DR   OrthoDB; 1557122at2759; -.
DR   PhylomeDB; Q9S7R5; -.
DR   PRO; PR:Q9S7R5; -.
DR   Proteomes; UP000006548; Chromosome 4.
DR   ExpressionAtlas; Q9S7R5; baseline and differential.
DR   Genevisible; Q9S7R5; AT.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0010022; P:meristem determinacy; IGI:TAIR.
DR   GO; GO:0009911; P:positive regulation of flower development; IMP:TAIR.
DR   CDD; cd00866; PEBP_euk; 1.
DR   Gene3D; 3.90.280.10; -; 1.
DR   InterPro; IPR008914; PEBP.
DR   InterPro; IPR036610; PEBP-like_sf.
DR   InterPro; IPR035810; PEBP_euk.
DR   InterPro; IPR001858; Phosphatidylethanolamine-bd_CS.
DR   PANTHER; PTHR11362; PTHR11362; 1.
DR   Pfam; PF01161; PBP; 1.
DR   SUPFAM; SSF49777; SSF49777; 1.
DR   PROSITE; PS01220; PBP; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..175
FT                   /note="Protein TWIN SISTER of FT"
FT                   /id="PRO_0000204763"
SQ   SEQUENCE   175 AA;  19688 MW;  5BDEBC89A2D3BB43 CRC64;
     MSLSRRDPLV VGSVVGDVLD PFTRLVSLKV TYGHREVTNG LDLRPSQVLN KPIVEIGGDD
     FRNFYTLVMV DPDVPSPSNP HQREYLHWLV TDIPATTGNA FGNEVVCYES PRPPSGIHRI
     VLVLFRQLGR QTVYAPGWRQ QFNTREFAEI YNLGLPVAAS YFNCQRENGC GGRRT